Mathematical descriptions of biochemical networks: Stability, stochasticity, evolution

In this paper, we review some fundamental aspects, as well as some new developments, in the emerging field of network biology. The focus of attention is placed on mathematical approaches to conceptual modeling of biomolecular networks with special emphasis on dynamic stability, stochasticity and evo...

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Bibliographic Details
Published in:Progress in biophysics and molecular biology 2011-08, Vol.106 (2), p.400-409
Main Author: Rosenfeld, Simon
Format: Article
Language:English
Subjects:
Biochemical networks
Biochemical Phenomena
Biological Evolution
Burstiness
Cellular Microenvironment
Computational Biology - methods
Computer Simulation
Dynamic stability
Humans
Models, Biological
Nonlinear Dynamics
S-Systems
Stochastic Processes
Stochasticity
Systems biology
Systems Biology - methods
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Summary:In this paper, we review some fundamental aspects, as well as some new developments, in the emerging field of network biology. The focus of attention is placed on mathematical approaches to conceptual modeling of biomolecular networks with special emphasis on dynamic stability, stochasticity and evolution.
ISSN:0079-6107
1873-1732
DOI:10.1016/j.pbiomolbio.2011.03.003