Botrytis cinerea Manipulates the Antagonistic Effects between Immune Pathways to Promote Disease Development in Tomato

Plants have evolved sophisticated mechanisms to sense and respond to pathogen attacks. Resistance against necrotrophic pathogens generally requires the activation of the jasmonic acid (JA) signaling pathway, whereas the salicylic acid (SA) signaling pathway is mainly activated against biotrophic pat...

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Bibliographic Details
Published in:The Plant cell 2011-06, Vol.23 (6), p.2405-2421
Main Authors: Oirdi, Mohamed El, Rahman, Taha Abd El, Rigano, Luciano, Hadrami, Abdelbasset El, Rodriguez, María Cecilia, Daayf, Fouad, Vojnov, Adrian, Bouarab, Kamal
Format: Article
Language:English
Subjects:
Anti-Infective Agents
Botrytis
Botrytis - metabolism
Botrytis - pathogenicity
Botrytis cinerea
Carbohydrate Conformation
Cyclopentanes - metabolism
Defensins - genetics
Defensins - metabolism
Glucans - chemistry
Glucans - metabolism
Immunity, Innate - immunology
Infections
Inoculation
Leaves
Lesions
Lycopersicon esculentum
Memory interference
Molecular Sequence Data
Oxylipins - metabolism
Pathogens
Plant cells
Plant Diseases - immunology
Plant Diseases - microbiology
Plant Leaves - immunology
Plant Leaves - microbiology
Plant Proteins - genetics
Plant Proteins - metabolism
Plants
Plants, Genetically Modified
RNA
Salicylic Acid - metabolism
Signal Transduction - immunology
Solanum
Solanum lycopersicum - genetics
Solanum lycopersicum - immunology
Solanum lycopersicum - microbiology
Tomatoes
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Summary:Plants have evolved sophisticated mechanisms to sense and respond to pathogen attacks. Resistance against necrotrophic pathogens generally requires the activation of the jasmonic acid (JA) signaling pathway, whereas the salicylic acid (SA) signaling pathway is mainly activated against biotrophic pathogens. SA can antagonize JA signaling and vice versa. Here, we report that the necrotrophic pathogen Botrytis cinerea exploits this antagonism as a strategy to cause disease development. We show that â. cinerea produces an exopolysaccharide, which acts as an elicitor of the SA pathway. In turn, the SA pathway antagonizes the JA signaling pathway, thereby allowing the fungus to develop its disease in tomato (Solanum lycopersicum). SA-promoted disease development occurs through Nonexpressed Pathogen Related1. We also show that the JA signaling pathway required for tomato resistance against B. cinerea is mediated by the systemin elicitor. These data highlight a new strategy used by cinerea to overcome the plant's defense system and to spread within the host.
ISSN:1040-4651
1532-298X
1532-298X
DOI:10.1105/tpc.111.083394