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An Interrupted Time Series Evaluation of a Hepatitis C Intervention for Persons with HIV

Accurate HCV knowledge is lacking among high-risk groups, including people with HIV/AIDS (PLWHA). Liver disease primarily due to HCV has emerged as a serious cause of mortality among PLWHA. We used an Interrupted Time Series design to evaluate a social-ecologically based intervention for PLWHA, wher...

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Bibliographic Details
Published in:AIDS and behavior 2011-11, Vol.15 (8), p.1721-1731
Main Authors: Proeschold-Bell, Rae Jean, Hoeppner, Bettina, Taylor, Baishakhi, Cohen, Sarah, Blouin, Rachel, Stringfield, Beth, Muir, Andrew J.
Format: Article
Language:English
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Summary:Accurate HCV knowledge is lacking among high-risk groups, including people with HIV/AIDS (PLWHA). Liver disease primarily due to HCV has emerged as a serious cause of mortality among PLWHA. We used an Interrupted Time Series design to evaluate a social-ecologically based intervention for PLWHA, where an infectious disease clinic serving a six-county intervention area was monitored before (7 months) and after (17 months) intervention onset. The intervention included education of PLWHA and medical providers, HIV/HCV support groups, and adaptation of the patient chart top sheet to include HCV test information. Clinic-level outcomes were assessed prospectively every other week for 2 years by interviewing patients ( n  = 259) with clinic appointments on assessment days. Abrupt, gradual and delayed intervention effects were tested. Weighted regression analyses showed higher average HCV knowledge and a higher prevalence of patients reporting HCV discussion with their medical providers after intervention onset. A delayed effect was found for HCV awareness, and a gradually increasing effect was found for knowing one’s HCV status. Other communities may consider adopting this intervention. Additional HCV interventions for PLWHA with HIV are needed.
ISSN:1090-7165
1573-3254
DOI:10.1007/s10461-010-9870-1