Loading…
Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine
Highlights ► EB peptide induces influenza virus aggregation and enhanced uptake by macrophages. ► Addition of the EB peptide to inactivated influenza vaccine enhances protection. ► EB adjuvant enhances IFN-γ production and cell-mediated immune responses.
Saved in:
| Published in: | Vaccine 2011-10, Vol.29 (44), p.7696-7703 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03 |
| container_end_page | 7703 |
| container_issue | 44 |
| container_start_page | 7696 |
| container_title | Vaccine |
| container_volume | 29 |
| creator | Jones, Jeremy C Settles, Erik W Brandt, Curtis R Schultz-Cherry, Stacey |
| description | Highlights ► EB peptide induces influenza virus aggregation and enhanced uptake by macrophages. ► Addition of the EB peptide to inactivated influenza vaccine enhances protection. ► EB adjuvant enhances IFN-γ production and cell-mediated immune responses. |
| doi_str_mv | 10.1016/j.vaccine.2011.07.133 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3190079</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0264410X11012023</els_id><sourcerecordid>898176611</sourcerecordid><originalsourceid>FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03</originalsourceid><addsrcrecordid>eNqFkk9v1DAQxSMEokvhIwCREOKUZcaO4_hShCr-SZU4lKLeLMeZZL2kzmJnVyqfHoddWuilJx_88_Ob9ybLniMsEbB6u17ujLXO05IB4hLkEjl_kC2wlrxgAuuH2QJYVRYlwuVR9iTGNQAIjupxdsSw5go5LrLL7y5sY276PlBvJuf7fEObybWUk18Zbynm04pyS8NQXFHrzERtHihuRh8pn8bc-W7Ykv9l8t0fqYOtp9mjzgyRnh3O4-zi44dvp5-Ls6-fvpy-PytsxcVUtEpWHa9brCTrGtPUVY0NKWKGKSmaVkrVMcFFaVE1vCQg1UGLwA1jQljgx9nJXnezbZI_S34KZtCb4K5MuNajcfr_G-9Wuh93OiUBIFUSeHMQCOPPLcVJX7k4j2s8jduoFTAuUm78XrJWNcqqQkzkqzvketwGn3LQWKoaVFWL-Wexp2wYYwzU3bhG0HPJeq0Paeq5ZA1SJxvp3Yt_R7559bfVBLw-ACZaM3Qh9ejiLVdWTEI9C73cc50ZtelDYi7O008CAEvGuEzEuz1BqcKdo6CjdZS2onWB7KTb0d1r9uSOgh2cd8nWD7qmeJuLjkyDPp93dl5ZTJosRc9_A5xR5l8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1498096859</pqid></control><display><type>article</type><title>Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine</title><source>ScienceDirect Journals</source><creator>Jones, Jeremy C ; Settles, Erik W ; Brandt, Curtis R ; Schultz-Cherry, Stacey</creator><creatorcontrib>Jones, Jeremy C ; Settles, Erik W ; Brandt, Curtis R ; Schultz-Cherry, Stacey</creatorcontrib><description>Highlights ► EB peptide induces influenza virus aggregation and enhanced uptake by macrophages. ► Addition of the EB peptide to inactivated influenza vaccine enhances protection. ► EB adjuvant enhances IFN-γ production and cell-mediated immune responses.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2011.07.133</identifier><identifier>PMID: 21839131</identifier><identifier>CODEN: VACCDE</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>additives ; Adjuvant ; adjuvants ; Adjuvants, Immunologic - administration & dosage ; Allergy and Immunology ; Animals ; antibodies ; Antibodies, Viral - blood ; antiviral properties ; Applied microbiology ; Avian flu ; Biological and medical sciences ; Cell-mediated immunity ; Colleges & universities ; Cytokines ; Eggs ; Female ; Fundamental and applied biological sciences. Psychology ; H5N1 influenza virus ; immune response ; Immune system ; Inactivated influenza vaccine ; influenza ; Influenza Vaccines - immunology ; Influenza virus ; interferon-gamma ; Interferon-gamma - metabolism ; Laboratory animals ; Leukocytes, Mononuclear - immunology ; Mice ; Mice, Inbred BALB C ; Microbiology ; Miscellaneous ; morbidity ; Mortality ; Orthomyxoviridae ; Orthomyxoviridae Infections - immunology ; Orthomyxoviridae Infections - pathology ; Orthomyxoviridae Infections - prevention & control ; Peptides ; Peptides - administration & dosage ; Phagocytosis ; Spleen - immunology ; splenocytes ; Sucrose ; Swine flu ; vaccination ; Vaccines ; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) ; Vaccines, Inactivated - immunology ; virion ; Virology ; Viruses</subject><ispartof>Vaccine, 2011-10, Vol.29 (44), p.7696-7703</ispartof><rights>Elsevier Ltd</rights><rights>2011 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Ltd. All rights reserved.</rights><rights>Copyright Elsevier Limited Oct 13, 2011</rights><rights>2011 Elsevier Ltd. All rights reserved. 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03</citedby><cites>FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24627083$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21839131$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jones, Jeremy C</creatorcontrib><creatorcontrib>Settles, Erik W</creatorcontrib><creatorcontrib>Brandt, Curtis R</creatorcontrib><creatorcontrib>Schultz-Cherry, Stacey</creatorcontrib><title>Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Highlights ► EB peptide induces influenza virus aggregation and enhanced uptake by macrophages. ► Addition of the EB peptide to inactivated influenza vaccine enhances protection. ► EB adjuvant enhances IFN-γ production and cell-mediated immune responses.</description><subject>additives</subject><subject>Adjuvant</subject><subject>adjuvants</subject><subject>Adjuvants, Immunologic - administration & dosage</subject><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>antibodies</subject><subject>Antibodies, Viral - blood</subject><subject>antiviral properties</subject><subject>Applied microbiology</subject><subject>Avian flu</subject><subject>Biological and medical sciences</subject><subject>Cell-mediated immunity</subject><subject>Colleges & universities</subject><subject>Cytokines</subject><subject>Eggs</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>H5N1 influenza virus</subject><subject>immune response</subject><subject>Immune system</subject><subject>Inactivated influenza vaccine</subject><subject>influenza</subject><subject>Influenza Vaccines - immunology</subject><subject>Influenza virus</subject><subject>interferon-gamma</subject><subject>Interferon-gamma - metabolism</subject><subject>Laboratory animals</subject><subject>Leukocytes, Mononuclear - immunology</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>morbidity</subject><subject>Mortality</subject><subject>Orthomyxoviridae</subject><subject>Orthomyxoviridae Infections - immunology</subject><subject>Orthomyxoviridae Infections - pathology</subject><subject>Orthomyxoviridae Infections - prevention & control</subject><subject>Peptides</subject><subject>Peptides - administration & dosage</subject><subject>Phagocytosis</subject><subject>Spleen - immunology</subject><subject>splenocytes</subject><subject>Sucrose</subject><subject>Swine flu</subject><subject>vaccination</subject><subject>Vaccines</subject><subject>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</subject><subject>Vaccines, Inactivated - immunology</subject><subject>virion</subject><subject>Virology</subject><subject>Viruses</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqFkk9v1DAQxSMEokvhIwCREOKUZcaO4_hShCr-SZU4lKLeLMeZZL2kzmJnVyqfHoddWuilJx_88_Ob9ybLniMsEbB6u17ujLXO05IB4hLkEjl_kC2wlrxgAuuH2QJYVRYlwuVR9iTGNQAIjupxdsSw5go5LrLL7y5sY276PlBvJuf7fEObybWUk18Zbynm04pyS8NQXFHrzERtHihuRh8pn8bc-W7Ykv9l8t0fqYOtp9mjzgyRnh3O4-zi44dvp5-Ls6-fvpy-PytsxcVUtEpWHa9brCTrGtPUVY0NKWKGKSmaVkrVMcFFaVE1vCQg1UGLwA1jQljgx9nJXnezbZI_S34KZtCb4K5MuNajcfr_G-9Wuh93OiUBIFUSeHMQCOPPLcVJX7k4j2s8jduoFTAuUm78XrJWNcqqQkzkqzvketwGn3LQWKoaVFWL-Wexp2wYYwzU3bhG0HPJeq0Paeq5ZA1SJxvp3Yt_R7559bfVBLw-ACZaM3Qh9ejiLVdWTEI9C73cc50ZtelDYi7O008CAEvGuEzEuz1BqcKdo6CjdZS2onWB7KTb0d1r9uSOgh2cd8nWD7qmeJuLjkyDPp93dl5ZTJosRc9_A5xR5l8</recordid><startdate>20111013</startdate><enddate>20111013</enddate><creator>Jones, Jeremy C</creator><creator>Settles, Erik W</creator><creator>Brandt, Curtis R</creator><creator>Schultz-Cherry, Stacey</creator><general>Elsevier Ltd</general><general>Elsevier</general><general>Elsevier Limited</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20111013</creationdate><title>Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine</title><author>Jones, Jeremy C ; Settles, Erik W ; Brandt, Curtis R ; Schultz-Cherry, Stacey</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>additives</topic><topic>Adjuvant</topic><topic>adjuvants</topic><topic>Adjuvants, Immunologic - administration & dosage</topic><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>antibodies</topic><topic>Antibodies, Viral - blood</topic><topic>antiviral properties</topic><topic>Applied microbiology</topic><topic>Avian flu</topic><topic>Biological and medical sciences</topic><topic>Cell-mediated immunity</topic><topic>Colleges & universities</topic><topic>Cytokines</topic><topic>Eggs</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>H5N1 influenza virus</topic><topic>immune response</topic><topic>Immune system</topic><topic>Inactivated influenza vaccine</topic><topic>influenza</topic><topic>Influenza Vaccines - immunology</topic><topic>Influenza virus</topic><topic>interferon-gamma</topic><topic>Interferon-gamma - metabolism</topic><topic>Laboratory animals</topic><topic>Leukocytes, Mononuclear - immunology</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>morbidity</topic><topic>Mortality</topic><topic>Orthomyxoviridae</topic><topic>Orthomyxoviridae Infections - immunology</topic><topic>Orthomyxoviridae Infections - pathology</topic><topic>Orthomyxoviridae Infections - prevention & control</topic><topic>Peptides</topic><topic>Peptides - administration & dosage</topic><topic>Phagocytosis</topic><topic>Spleen - immunology</topic><topic>splenocytes</topic><topic>Sucrose</topic><topic>Swine flu</topic><topic>vaccination</topic><topic>Vaccines</topic><topic>Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)</topic><topic>Vaccines, Inactivated - immunology</topic><topic>virion</topic><topic>Virology</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jones, Jeremy C</creatorcontrib><creatorcontrib>Settles, Erik W</creatorcontrib><creatorcontrib>Brandt, Curtis R</creatorcontrib><creatorcontrib>Schultz-Cherry, Stacey</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jones, Jeremy C</au><au>Settles, Erik W</au><au>Brandt, Curtis R</au><au>Schultz-Cherry, Stacey</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2011-10-13</date><risdate>2011</risdate><volume>29</volume><issue>44</issue><spage>7696</spage><epage>7703</epage><pages>7696-7703</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><coden>VACCDE</coden><abstract>Highlights ► EB peptide induces influenza virus aggregation and enhanced uptake by macrophages. ► Addition of the EB peptide to inactivated influenza vaccine enhances protection. ► EB adjuvant enhances IFN-γ production and cell-mediated immune responses.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>21839131</pmid><doi>10.1016/j.vaccine.2011.07.133</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2011-10, Vol.29 (44), p.7696-7703 |
| issn | 0264-410X 1873-2518 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3190079 |
| source | ScienceDirect Journals |
| subjects | additives Adjuvant adjuvants Adjuvants, Immunologic - administration & dosage Allergy and Immunology Animals antibodies Antibodies, Viral - blood antiviral properties Applied microbiology Avian flu Biological and medical sciences Cell-mediated immunity Colleges & universities Cytokines Eggs Female Fundamental and applied biological sciences. Psychology H5N1 influenza virus immune response Immune system Inactivated influenza vaccine influenza Influenza Vaccines - immunology Influenza virus interferon-gamma Interferon-gamma - metabolism Laboratory animals Leukocytes, Mononuclear - immunology Mice Mice, Inbred BALB C Microbiology Miscellaneous morbidity Mortality Orthomyxoviridae Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - pathology Orthomyxoviridae Infections - prevention & control Peptides Peptides - administration & dosage Phagocytosis Spleen - immunology splenocytes Sucrose Swine flu vaccination Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Inactivated - immunology virion Virology Viruses |
| title | Virus aggregating peptide enhances the cell-mediated response to influenza virus vaccine |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T12%3A08%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Virus%20aggregating%20peptide%20enhances%20the%20cell-mediated%20response%20to%20influenza%20virus%20vaccine&rft.jtitle=Vaccine&rft.au=Jones,%20Jeremy%20C&rft.date=2011-10-13&rft.volume=29&rft.issue=44&rft.spage=7696&rft.epage=7703&rft.pages=7696-7703&rft.issn=0264-410X&rft.eissn=1873-2518&rft.coden=VACCDE&rft_id=info:doi/10.1016/j.vaccine.2011.07.133&rft_dat=%3Cproquest_pubme%3E898176611%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c635t-d976f38d1672fbab8681be9e2a2975bd779f25354c19b34e0e9f0d103a2255c03%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1498096859&rft_id=info:pmid/21839131&rfr_iscdi=true |