Intestinal innate immunity and the pathogenesis of Salmonella enteritis

Acute gastroenteritis caused by Salmonella typhimurium infection is a clinical problem with significant public health impact. The availability of several experimental models of this condition has allowed detailed investigation of the cellular and molecular interactions involved in its pathogenesis....

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Bibliographic Details
Published in:Immunologic research 2007, Vol.37 (1), p.61-77
Main Authors: Srikanth, Chittur V, Cherayil, Bobby J
Format: Article
Language:English
Subjects:
Animals
Bacterial infections
Gastroenteritis - immunology
Gastroenteritis - microbiology
Gastrointestinal diseases
Humans
Immunity, Innate
Immunology
Inflammation - immunology
Inflammation - microbiology
Intestines - immunology
Intestines - microbiology
Mice
Pathology
Salmonella
Salmonella Infections - immunology
Salmonella Infections - microbiology
Salmonella typhimurium
Salmonella typhimurium - pathogenicity
Virulence
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Summary:Acute gastroenteritis caused by Salmonella typhimurium infection is a clinical problem with significant public health impact. The availability of several experimental models of this condition has allowed detailed investigation of the cellular and molecular interactions involved in its pathogenesis. Such studies have shed light on the roles played by bacterial virulence factors and host innate immune mechanisms in the development of intestinal inflammation.
ISSN:0257-277X
1559-0755
DOI:10.1007/BF02686090