Beta 2 antagonism in acute respiratory failure

Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this eviden...

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Bibliographic Details
Published in:Critical care (London, England) England), 2010, Vol.14 (6), p.1012-1012
Main Authors: Mac Sweeney, Rob, Devereaux, P J, McAuley, Daniel F
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - administration & dosage
Female
Hospital Mortality - trends
Humans
Intensive Care Units
Male
Respiratory Insufficiency - drug therapy
Respiratory Insufficiency - mortality
Online Access:Get full text
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Summary:Post hoc analyses from the B-type natriuretic peptide for Acute Shortness of Breath Evaluation (BASEL)-II-ICU study suggest an association between beta-blocker usage at admission and improved mortality in patients treated in the intensive care unit for acute respiratory failure. Although this evidence is encouraging, there is a need for a phase 2 proof-of-concept randomized controlled trial of beta-blocker therapy in patients admitted with acute respiratory failure.
ISSN:1364-8535
1466-609X
DOI:10.1186/cc9359