Increased oxidative stress in patients with familial Mediterranean fever during attack period

Objectives: We aimed to investigate the status of oxidant and antioxidants during attack period (AP) and attack free periods (AFP) in Familial Mediterranean fever (FMF) patients. Methods: Measured the levels of malondialdehyde (MDA), protein carbonyl (PC), glutathione (GSH) and antioxidant vitamins...

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Bibliographic Details
Published in:African health sciences 2011-08, Vol.11 (3), p.S6-S13
Main Authors: Ediz, L, Ozkol, H, Tekeoglu, I, Tuluce, Y, Gulcu, E, Koyuncu, I
Format: Article
Language:English
Subjects:
Acute Disease
Adult
Antioxidant enzymes, Antioxidant vitamins, Familial Mediterranean fever, Lipid peroxidation, Protein oxidation
Antioxidants
Disease management
Familial Mediterranean Fever - blood
Familial Mediterranean Fever - metabolism
Female
Fever
Health and Medicine
Humans
Male
Oxidation
Oxidative Stress - physiology
Vitamins
Young Adult
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Summary:Objectives: We aimed to investigate the status of oxidant and antioxidants during attack period (AP) and attack free periods (AFP) in Familial Mediterranean fever (FMF) patients. Methods: Measured the levels of malondialdehyde (MDA), protein carbonyl (PC), glutathione (GSH) and antioxidant vitamins (A,C and E) as well as the activities of catalase (CAT) and glutathione peroxidase (GSH-Px) in serum and whole blood of FMF patients in FMF-AP and FMF-AFP. Results: Levels of MDA and PC were found significantly higher (p
ISSN:1680-6905
1729-0503
1680-6905
DOI:10.4314/ahs.v11i3.70063