New Generations： Sequencing Machines and Their Computational Challenges

New generation sequencing systems are changing how molecular biology is practiced. The widely promoted $1000 genome will be a reality with attendant changes for healthcare, including personalized medicine. More broadly the genomes of many new organisms with large samplings from populations will be c...

Full description

Saved in:
Bibliographic Details
Published in:Journal of computer science and technology 2010, Vol.25 (1), p.3-9
Main Authors: Schwartz, David C., Waterman, Michael S.
Format: Article
Language:English
Subjects:
Artificial Intelligence
Cloning
Computation
Computer Science
Data Structures and Information Theory
Demand
DNA polymerase
Explosions
Genetic testing
Genomes
Information Systems Applications (incl.Internet)
Marketing
Molecular biology
Organisms
Sampling
Sequencing
Software Engineering
Survey
Theory of Computation
个性化医疗
分子生物学
卫生保健
基因组
抽样调查
计算方法
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:New generation sequencing systems are changing how molecular biology is practiced. The widely promoted $1000 genome will be a reality with attendant changes for healthcare, including personalized medicine. More broadly the genomes of many new organisms with large samplings from populations will be commonplace. What is less appreciated is the explosive demands on computation, both for CPU cycles and storage as well as the need for new computational methods. In this article we will survey some of these developments and demands.
ISSN:1000-9000
1860-4749
DOI:10.1007/s11390-010-9300-x