Association of Glucocorticoid Use and Low 25-Hydroxyvitamin D Levels: Results from the National Health and Nutrition Examination Survey (NHANES): 2001–2006

Context: In many disorders requiring steroid therapy, there is substantial decrease in bone mineral density. The association between steroid use and 25-hydroxyvitamin D [25(OH)D] deficiency has not been confirmed in large population-based studies, and currently there are no specific vitamin D recomm...

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Published in:The journal of clinical endocrinology and metabolism 2011-12, Vol.96 (12), p.3838-3845
Main Authors: Skversky, Amy L, Kumar, Juhi, Abramowitz, Matthew K, Kaskel, Frederick J, Melamed, Michal L
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Child
Child, Preschool
Cross-Sectional Studies
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrine Research
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Glucocorticoids - adverse effects
Glucocorticoids - therapeutic use
Humans
Infant
Male
Medical sciences
Middle Aged
Nutrition Surveys
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - chemically induced
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Summary:Context: In many disorders requiring steroid therapy, there is substantial decrease in bone mineral density. The association between steroid use and 25-hydroxyvitamin D [25(OH)D] deficiency has not been confirmed in large population-based studies, and currently there are no specific vitamin D recommendations for steroid users. Objective: The aim of the study was to evaluate the association of serum 25(OH)D deficiency [defined as 25(OH)D
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2011-1600