Cryopreservation and Fertility : Current and Prospective Possibilities for Female Cancer Patients

With the evolution of the treatment of malignant neoplasms, the survival rates of patients undergoing chemo- or radiotherapy are increasing. The continuous development of techniques of assisted human reproduction has led to important strategies in an attempt to maintain reproductive function in pati...

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Bibliographic Details
Published in:ISRN obstetrics and gynecology 2011-01, Vol.2011 (2011), p.1-7
Main Authors: Campos, Jacira Ribeiro, Rosa-e-Silva, Ana Carolina Japur de Sá
Format: Article
Language:English
Subjects:
Review
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Summary:With the evolution of the treatment of malignant neoplasms, the survival rates of patients undergoing chemo- or radiotherapy are increasing. The continuous development of techniques of assisted human reproduction has led to important strategies in an attempt to maintain reproductive function in patients subjected to treatment of neoplastic diseases, among them cryopreservation of embryos, gametes, and ovarian cortical tissue. The freezing of ovarian tissue is currently being proposed with the primary purpose of preserving ovarian function in these patients. Currently, the major challenge of groups working with preservation of fertility is the use of cryopreserved ovarian tissue after disease remission. The main alternatives presented today are the implantation of hetero- or orthotopic tissue and isolation of immature follicles from ovarian tissue followed by in vitro maturation and assisted reproduction procedures.
ISSN:2090-4436
2090-4444
DOI:10.5402/2011/350813