The Effect of Multidisciplinary Lifestyle Intervention on the Pre- and Postprandial Plasma Gut Peptide Concentrations in Children with Obesity

Objective. This study aims to evaluate the effect of a multidisciplinary treatment of obesity on plasma concentrations of several gut hormones in fasting condition and in response to a mixed meal in children. Methods. Complete data were available from 36 obese children (age 13.3±2.0 yr). At baseline...

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Bibliographic Details
Published in:ISRN endocrinology 2011-01, Vol.2011 (2011), p.1-7
Main Authors: Vos, Rimke C., Pijl, Hanno, Wit, Jan M., van Zwet, Erik W., van der Bent, Chris, Houdijk, Euphemia C. A. M.
Format: Article
Language:English
Subjects:
Behavior
Children & youth
Food
Hormones
Hypothyroidism
Lifestyles
Medical statistics
Meetings
Obesity
Pediatrics
Plasma
Studies
Weight control
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Summary:Objective. This study aims to evaluate the effect of a multidisciplinary treatment of obesity on plasma concentrations of several gut hormones in fasting condition and in response to a mixed meal in children. Methods. Complete data were available from 36 obese children (age 13.3±2.0 yr). At baseline and after the 3-month multidisciplinary treatment, fasting and postprandial blood samples were taken for glucose, insulin, ghrelin, peptide YY (PYY), and glucagon-like peptide 1 (GLP-1). Results. BMI-SDS was significantly reduced by multidisciplinary treatment (from 4.2±0.7 to 4.0±0.9, P
ISSN:2090-4630
2090-4649
DOI:10.5402/2011/353756