Contact Is Repulsive, but Please Note the “Enclosed”

Previous models of neuronal dendrite arborization suggested that contact-dependent self-avoidance between dendrite branches prevents self-crossings within the arbor. Two papers in Neuron show how integrin-mediated adhesion to the extracellular matrix restricts dendrites to a two-dimensional space to...

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Bibliographic Details
Published in:Developmental cell 2012-01, Vol.22 (1), p.5-6
Main Authors: Burgess, Robert W., Garrett, Andrew M., Tadenev, Abigail L.D.
Format: Article
Language:English
Citations: Items that this one cites
Online Access:Get full text
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Summary:Previous models of neuronal dendrite arborization suggested that contact-dependent self-avoidance between dendrite branches prevents self-crossings within the arbor. Two papers in Neuron show how integrin-mediated adhesion to the extracellular matrix restricts dendrites to a two-dimensional space to optimize this mechanism (Han et al., 2012; Kim et al., 2012).
ISSN:1534-5807
1878-1551
DOI:10.1016/j.devcel.2011.12.017