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Adjunctive daily supplementation with encapsulated fruit, vegetable and berry juice powder concentrates and clinical periodontal outcomes: a double-blind RCT

Aim A double‐blind randomized controlled trial to determine whether dietary supplementation with fruit/vegetable/berry juice powder concentrates, simultaneously with non‐surgical periodontal therapy, improved 2‐month treatment outcomes. Methods Volunteers with chronic periodontitis were randomly ass...

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Bibliographic Details
Published in:Journal of clinical periodontology 2012-01, Vol.39 (1), p.62-72
Main Authors: Chapple, Iain L. C., Milward, Michael R., Ling-Mountford, Nicola, Weston, Paul, Carter, Kevin, Askey, Keeley, Dallal, Gerard E., De Spirt, Silke, Sies, Helmut, Patel, Dina, Matthews, John B.
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Language:English
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Summary:Aim A double‐blind randomized controlled trial to determine whether dietary supplementation with fruit/vegetable/berry juice powder concentrates, simultaneously with non‐surgical periodontal therapy, improved 2‐month treatment outcomes. Methods Volunteers with chronic periodontitis were randomly assigned to one of three groups: fruit/vegetable (FV), fruit/vegetable/berry (FVB) or placebo. Supplements were taken daily during non‐surgical debridement and maintenance and outcomes assessed at 2, 5 and 8 months after completion. Primary outcomes were mean probing pocket depth (PPD), clinical attachment gain, % sites bleeding on probing (% BOP) at 2 months. Adherence and plasma β‐carotene were determined. Results Sixty‐one nutritionally replete (by serum biochemistry) volunteers enrolled and 60 (n = 20 per arm) completed the 2‐month review. Clinical outcomes improved in all groups at 2 months, with additional improvement in PPD versus placebo for FV (p 
ISSN:0303-6979
1600-051X
DOI:10.1111/j.1600-051X.2011.01793.x