Dicer Functions in Aquatic Species

Dicer is an RNase III enzyme with two catalytic subunits, which catalyzes the cleavage of double-stranded RNA to small interfering RNAs and micro-RNAs, which are mainly involved in invasive nucleic acid defense and endogenous genes regulation. Dicer is abundantly expressed in embryos, indicating the...

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Bibliographic Details
Published in:Journal of amino acids 2011-01, Vol.2011 (2011), p.1-5
Main Authors: Kitagishi, Yasuko, Okumura, Naoko, Yoshida, Hitomi, Tateishi, Chika, Nishimura, Yuri, Matsuda, Satoru
Format: Article
Language:English
Subjects:
Review
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Summary:Dicer is an RNase III enzyme with two catalytic subunits, which catalyzes the cleavage of double-stranded RNA to small interfering RNAs and micro-RNAs, which are mainly involved in invasive nucleic acid defense and endogenous genes regulation. Dicer is abundantly expressed in embryos, indicating the importance of the protein in early embryonic development. In addition, Dicer is thought to be involved in defense mechanism against foreign nucleic acids such as viruses. This paper will mainly focus on the recent progress of Dicer-related research and discuss potential RNA interference pathways in aquatic species.
ISSN:2090-0104
2090-0112
2090-0112
DOI:10.4061/2011/782187