Posttranslational regulation of AMPA receptor trafficking and function

Highlights ► AMPA receptor phosphorylation regulates receptor trafficking and function. ► AMPA receptor palmitoylation plays differential roles in receptor trafficking. ► AMPA receptor ubiquitination functions in receptor endocytosis and degradation. ► Posttranslational modifications interact with e...

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Bibliographic Details
Published in:Current opinion in neurobiology 2012-06, Vol.22 (3), p.470-479
Main Authors: Lu, Wei, Roche, Katherine W
Format: Article
Language:English
Subjects:
Animals
Models, Biological
Neurology
Protein Biosynthesis - physiology
Protein Transport - physiology
Psychiatry
Receptors, AMPA - physiology
Synapses - metabolism
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Summary:Highlights ► AMPA receptor phosphorylation regulates receptor trafficking and function. ► AMPA receptor palmitoylation plays differential roles in receptor trafficking. ► AMPA receptor ubiquitination functions in receptor endocytosis and degradation. ► Posttranslational modifications interact with each other to modulate AMPA receptors.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2011.09.008