Identifying biological themes within lists of genes with EASE

EASE is a customizable software application for rapid biological interpretation of gene lists that result from the analysis of microarray, proteomics, SAGE and other high-throughput genomic data. The biological themes returned by EASE recapitulate manually determined themes in previously published g...

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Bibliographic Details
Published in:Genome biology 2003-01, Vol.4 (10), p.R70-R70, Article R70
Main Authors: Hosack, Douglas A, Dennis, Jr, Glynn, Sherman, Brad T, Lane, H Clifford, Lempicki, Richard A
Format: Article
Language:English
Subjects:
Computational Biology - methods
Databases, Genetic
Genes - physiology
Genomics - methods
Internet
Oligonucleotide Array Sequence Analysis
Proteomics
Software
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Description
Summary:EASE is a customizable software application for rapid biological interpretation of gene lists that result from the analysis of microarray, proteomics, SAGE and other high-throughput genomic data. The biological themes returned by EASE recapitulate manually determined themes in previously published gene lists and are robust to varying methods of normalization, intensity calculation and statistical selection of genes. EASE is a powerful tool for rapidly converting the results of functional genomics studies from 'genes' to 'themes'.
ISSN:1474-760X
1465-6906
1474-760X
1465-6914
DOI:10.1186/gb-2003-4-10-r70