In vitro evaluation of anthelmintic property of ethno-veterinary plant extracts against the liver fluke Fasciola gigantica

The present study was envisaged to evaluate the efficacy of ethno-medicinal plant aqueous extracts such as Allium sativum , Lawsonia inermis , and Opuntia ficus indica in vitro in comparison with the chemotherapeutic agent, Oxyclozanide on Fasciola gigantica adults. The efficacy was evaluated by gro...

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Bibliographic Details
Published in:Journal of parasitic diseases 2012-04, Vol.36 (1), p.26-30
Main Authors: Jeyathilakan, N., Murali, K., Anandaraj, A., Abdul Basith, S.
Format: Article
Language:English
Subjects:
Health Promotion and Disease Prevention
Infectious Diseases
Medicine
Medicine & Public Health
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Summary:The present study was envisaged to evaluate the efficacy of ethno-medicinal plant aqueous extracts such as Allium sativum , Lawsonia inermis , and Opuntia ficus indica in vitro in comparison with the chemotherapeutic agent, Oxyclozanide on Fasciola gigantica adults. The efficacy was evaluated by gross visual motility and mortality of F. gigantica with score index, light microscopic examination of carmine stained flukes and histopathology of treated flukes. Based on the in vitro trials conducted using above plant extracts at 1 percent, 2.5 percent and 5 percent concentration, the extracts of O. ficus indica showed flukicidal effect at 2.5 and 5% concentration . However A. sativum and L. inermis were effective at 5% concentration only. The study indicated the potential for developing herbal-based anthelmintics to control F . gigantica in livestock .
ISSN:0971-7196
0975-0703
DOI:10.1007/s12639-011-0064-1