Overweight children with type 1 diabetes have a more favourable lipid profile than overweight non-diabetic children

In the present article, we aimed to compare the cardiometabolic risk between overweight children with and without type 1 diabetes (T1DM). Therefore, data with regard to cardiometabolic risk parameters of 44 overweight Caucasian children (3–18 years) with T1DM were matched with 44 overweight peers wi...

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Bibliographic Details
Published in:European journal of pediatrics 2012-03, Vol.171 (3), p.493-498
Main Authors: van Vliet, Mariska, van der Heyden, Josine C., Diamant, Michaela, von Rosenstiel, Inès A., Schindhelm, Roger K., Heymans, Martijn W., Brandjes, Desiderius P. M., Beijnen, Jos H., Aanstoot, Henk J., Veeze, Henk J.
Format: Article
Language:English
Subjects:
Adolescent
Alanine Transaminase - blood
Biological and medical sciences
Biomarkers - blood
Blood pressure
Cardiovascular disease
Cardiovascular Diseases - etiology
Case-Control Studies
Child
Child, Preschool
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 1 - blood
Diabetes Mellitus, Type 1 - complications
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Ethnicity
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Family medical history
Fasting
Female
General aspects
Glycated Hemoglobin A - metabolism
Hospitals
Humans
Hypertension
Internal medicine
Lipids
Male
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Obesity
Original Paper
Overweight
Overweight - blood
Overweight - complications
Pediatrics
Risk Factors
Triglycerides - blood
Waist Circumference
White people
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Summary:In the present article, we aimed to compare the cardiometabolic risk between overweight children with and without type 1 diabetes (T1DM). Therefore, data with regard to cardiometabolic risk parameters of 44 overweight Caucasian children (3–18 years) with T1DM were matched with 44 overweight peers without T1DM for sex, ethnicity, age and standard deviation score of BMI (Z-BMI). Detailed history was taken, information regarding anthropometrics and family history were collected and blood pressure was measured. Blood samples were collected for evaluation of lipid profiles (fasting in controls, non-fasting in T1DM children), alanine aminotransferase and HbA1c (in children with T1DM). It was found that overweight children with T1DM had lower median standard deviation score of waist circumference (Z-WC) as compared to the overweight control group [median, 2.0 (interquartile range, IQR, 1.5–2.3) vs. 2.6 (IQR, 2.0–2.9), P  
ISSN:0340-6199
1432-1076
DOI:10.1007/s00431-011-1574-7