Prognostic Biomarkers and EBV Infection Research in Diffuse Large B-Cell Lymphoma of the Palatine Tonsils

Diffuse large B-cell lymphoma represents approximately 30%–40% of all diagnoses of non-Hodgkin’s Lymphoma and may represent up to 80% of all lymphomas that arise in the palatine tonsils. Several studies have attempted to correlate clinical, laboratorial, and tissue factors with the prognosis of the...

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Published in:ISRN oncology 2012, Vol.2012 (2012), p.1-7
Main Authors: Marques, Marinho, Luz, Estela, Hummel, Michael, Vieira, Maria das Graças Silva, Bahia, Regina Célia, Oliveira, Maria Cristina, Netto, Eduardo Martins, Luz, Ivana, Araújo, Iguaracyra
Format: Article
Language:English
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Summary:Diffuse large B-cell lymphoma represents approximately 30%–40% of all diagnoses of non-Hodgkin’s Lymphoma and may represent up to 80% of all lymphomas that arise in the palatine tonsils. Several studies have attempted to correlate clinical, laboratorial, and tissue factors with the prognosis of the lymphomas, such as the International Prognostic Index, the tissue expression of some proteins, and the lymphocyte count at the time of diagnosis, as well as to correlate Epstein-Barr virus (EBV) infection with worse prognoses. Patients with palatine tonsil DLBCL, from Salvador, Bahia, Brazil, were studied in order to identify prognostic factors. Twenty-four patients with DLBCL were studied. The factors that negatively influenced the patients’ survival rates were the lymphocyte count at the time of diagnosis
ISSN:2090-5661
2090-567X
2090-567X
DOI:10.5402/2012/652682