Obstetric and perinatal outcomes in pregnancies complicated by Type 1 and Type 2 diabetes: influences of glycaemic control, obesity and social disadvantage

Diabet. Med. 28, 1060–1067 (2011) Aims  To compare obstetric and perinatal outcomes in women with Type 1 and Type 2 diabetes and relate these to maternal risk factors. Methods  Prospective cohort study of 682 consecutive diabetic pregnancies in East Anglia during 2006–2009. Relationships between con...

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Bibliographic Details
Published in:Diabetic medicine 2011-09, Vol.28 (9), p.1060-1067
Main Authors: Murphy, H. R., Steel, S. A., Roland, J. M., Morris, D., Ball, V., Campbell, P. J., Temple, R. C.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cohort Studies
Congenital Abnormalities - epidemiology
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - epidemiology
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Glycated Hemoglobin - metabolism
Humans
Infant, Newborn
large for gestational age
macrosomia
Maternal Age
Medical sciences
Obesity - complications
Obesity - epidemiology
Pregnancy
Pregnancy in Diabetics - epidemiology
Pregnancy Outcome
Prospective Studies
Risk Factors
Socioeconomic Factors
Type 1 diabetes
Type 2 diabetes
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vertebrates: endocrinology
Young Adult
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Summary:Diabet. Med. 28, 1060–1067 (2011) Aims  To compare obstetric and perinatal outcomes in women with Type 1 and Type 2 diabetes and relate these to maternal risk factors. Methods  Prospective cohort study of 682 consecutive diabetic pregnancies in East Anglia during 2006–2009. Relationships between congenital malformation, perinatal mortality and perinatal morbidity (large for gestational age, preterm delivery, neonatal care) with maternal age, parity, ethnicity, glycaemic control, obesity and social disadvantage were examined using bivariable and multivariate models. Results  There were 408 (59.8%) Type 1 and 274 (40.2%) Type 2 diabetes pregnancies. Women with Type 2 diabetes were older (P 
ISSN:0742-3071
1464-5491
DOI:10.1111/j.1464-5491.2011.03333.x