DNA origami: a quantum leap for self-assembly of complex structures

The spatially controlled positioning of functional materials by self-assembly is one of the fundamental visions of nanotechnology. Major steps towards this goal have been achieved using DNA as a programmable building block. This tutorial review will focus on one of the most promising methods: DNA or...

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Bibliographic Details
Published in:Chemical Society reviews 2011-01, Vol.40 (12), p.5636-5646
Main Authors: Tørring, Thomas, Voigt, Niels V, Nangreave, Jeanette, Yan, Hao, Gothelf, Kurt V
Format: Article
Language:English
Subjects:
DNA - chemistry
Humans
Nanotechnology - methods
Nucleic Acid Conformation
Robotics
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Summary:The spatially controlled positioning of functional materials by self-assembly is one of the fundamental visions of nanotechnology. Major steps towards this goal have been achieved using DNA as a programmable building block. This tutorial review will focus on one of the most promising methods: DNA origami. The basic design principles, organization of a variety of functional materials and recent implementation of DNA robotics are discussed together with future challenges and opportunities.
ISSN:0306-0012
1460-4744
DOI:10.1039/c1cs15057j