The sequence of an adrenal specific human cDNA, pG2

We previously reported the isolation of a cDNA clone, pG2, from a human pheochromocytoma, a tumor of mature adrenal chromaffin cells. We have now isolated a full length cDNA from a human adrenal cDNA library. The clone contains 1557 bp insert and a poly A tail of 73 bp that corresponds closely in si...

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Bibliographic Details
Published in:Nucleic acids research 1990-02, Vol.18 (3), p.685-685
Main Authors: HELMAN, L. J, SACK, N, PLON, S. E, ISRAEL, M. A
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - analysis
Adrenal Glands - analysis
Amino Acid Sequence
Base Sequence
Biological and medical sciences
chromaffin cells
DNA - genetics
Fundamental and applied biological sciences. Psychology
Gene Expression
Genes. Genome
Humans
man
Molecular and cellular biology
Molecular genetics
Molecular Sequence Data
Pheochromocytoma - analysis
RNA, Messenger - analysis
RNA, Messenger - genetics
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Summary:We previously reported the isolation of a cDNA clone, pG2, from a human pheochromocytoma, a tumor of mature adrenal chromaffin cells. We have now isolated a full length cDNA from a human adrenal cDNA library. The clone contains 1557 bp insert and a poly A tail of 73 bp that corresponds closely in size to the 1.6 kb mRNA recognized by pG2. The nucleotide sequence is not homologous to any previously reported sequences. The predicted protein encoded by pG2 contains 286 amino acids with a predicted molecular weight of approximately 30,600 daltons.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/18.3.685