MspI polymorphism at the human complement component C6 gene (C6)

The human Complement component C6 and C7 genes are closely linked. A C7 RFLP (TaqI) has been described. Analyses of 80 haplotypes showed that both loci are in linkage disequilibrium for these RFLPs. Significant association between alleles C6 B1-C7 4.0 and C6 B2-C7 4.2 exists in the Spanish populatio...

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Bibliographic Details
Published in:Nucleic acids research 1991-01, Vol.19 (1), p.194-194
Main Authors: Coto, E, Domínguez, O, Martínez-Naves, E, Setién, F, Gutiérrez, V, López-Larrea, C
Format: Article
Language:English
Subjects:
Chromosome Mapping
Chromosomes, Human, Pair 5
Complement C6 - genetics
Deoxyribonuclease HpaII
Deoxyribonucleases, Type II Site-Specific - metabolism
Female
Human DNA Markers
Humans
Male
Pedigree
Polymorphism, Restriction Fragment Length
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Summary:The human Complement component C6 and C7 genes are closely linked. A C7 RFLP (TaqI) has been described. Analyses of 80 haplotypes showed that both loci are in linkage disequilibrium for these RFLPs. Significant association between alleles C6 B1-C7 4.0 and C6 B2-C7 4.2 exists in the Spanish population.
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/19.1.194