Variability in cardiovascular functions and baroflex sensitivity following inhalation of petroleum hydrocarbons

Objective: Although petroleum products are useful chemical compounds which form an intégral part of our modern technology, they have been reported to cause deleterious effect on health following their inhalation. Petroleum hydrocarbons-dependent health hazards and their mechanisms have been associat...

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Bibliographic Details
Published in:Journal of cardiovascular disease research 2012-04, Vol.3 (2), p.99-103
Main Authors: Azeez, O.M., Akhigbe, R.E., Ige, S.F., Saka, W.A., Anigbogu, C.N.
Format: Article
Language:English
Subjects:
Animals
Arterial occlusions
baroreflex sensitivity
Blood pressure
Body weight
Cardiovascular system
Care and treatment
Diagnosis
Drinking water
Food contamination & poisoning
Health aspects
heart rate
Hydrocarbons
Hypoxia
mean arterial pressure
Original
Petroleum
petroleum hydrocarbons
Reflexes
Rodents
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Summary:Objective: Although petroleum products are useful chemical compounds which form an intégral part of our modern technology, they have been reported to cause deleterious effect on health following their inhalation. Petroleum hydrocarbons-dependent health hazards and their mechanisms have been associated with the routes of administration. This study, therefore, aimed at the isolation and chemical characterization of various petroleum products, and also investigating in rat model of Sprague dawley strain, the variability in cardiovascular functions and possible mechanism following inhalation of petroleum products. Materials and Methods: Control rats were not exposed to any form of petroleum products, while the petrol-exposed, diesel-exposed, and kerosene-exposed were exposed to petrol, diesel, and kerosene respectively. Results: When compared with the controls, all exposed groups showed a significant (P
ISSN:0975-3583
0976-2833
DOI:10.4103/0975-3583.95361