Fatal encephalitis associated with novel influenza A (H1N1) virus infection in a child

A 4-year-old girl presented with fever, coughing, and vomiting; followed by unconsciousness. Magnetic resonance imaging showed hyperintense changes in the thalami bilaterally, brain stem, cerebellum, and subcortical cortex. Novel influenza A (H1N1) virus was identified by polymerase chain reaction i...

Full description

Saved in:
Bibliographic Details
Published in:Neurological sciences 2012-06, Vol.33 (3), p.677-679
Main Authors: Incecik, Faruk, Ozlem Hergüner, M., Altunbasak, Sakir, Yıldızdas, Dincer, Antmen, Bülent, Özgür, Özden, Özgür, Özlem
Format: Article
Language:English
Subjects:
Brain - pathology
Brain - virology
Brain stem
Case Report
Cerebellum
Child, Preschool
Cortex
Differential diagnosis
Encephalitis
Encephalitis, Viral - etiology
Fatal Outcome
Female
Fever
Humans
Infection
Influenza A
Influenza A Virus, H1N1 Subtype - pathogenicity
Influenza, Human - complications
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Polymerase chain reaction
Psychiatry
Seizures
Vomiting
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 4-year-old girl presented with fever, coughing, and vomiting; followed by unconsciousness. Magnetic resonance imaging showed hyperintense changes in the thalami bilaterally, brain stem, cerebellum, and subcortical cortex. Novel influenza A (H1N1) virus was identified by polymerase chain reaction in patient’s nasopharyngeal swab specimen. We reported a rare case of clinically severe, novel influenza A-associated encephalitis. Novel influenza A should be considered in the differential diagnosis in patients with seizures and mental status changes, especially during an influenza outbreak.
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-011-0839-2