Dabigatran in patients with atrial fibrillation: perioperative and periinterventional management

Summary In any type of invasive surgery, the patient’s individual risk of thromboembolism has to be weighed against the risk of bleeding. Based on various everyday situations in clinical routine, the purpose of the present expert recommendations is to provide appropriate perioperative and periinterv...

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Bibliographic Details
Published in:Wiener Klinische Wochenschrift 2012-05, Vol.124 (9-10), p.340-347
Main Authors: Weltermann, A., Brodmann, M., Domanovits, H., Eber, B., Gottsauner-Wolf, M., Halbmayer, W. M., Hiesmayr, J. M., Kyrle, P. A., Längle, F., Roithinger, F. X., Watzke, H., Windhager, R., Wolf, C., Zweiker, R.
Format: Article
Language:English
Subjects:
Atrial Fibrillation - drug therapy
Atrial Fibrillation - surgery
Austria
Benzimidazoles - adverse effects
Benzimidazoles - therapeutic use
beta-Alanine - adverse effects
beta-Alanine - analogs & derivatives
beta-Alanine - therapeutic use
Consensus Report
Dabigatran
Endocrinology
Female
Gastroenterology
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Perioperative Care - methods
Perioperative Care - standards
Pneumology/Respiratory System
Postoperative Hemorrhage - chemically induced
Postoperative Hemorrhage - prevention & control
Practice Guidelines as Topic
Premedication - methods
Premedication - standards
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Summary:Summary In any type of invasive surgery, the patient’s individual risk of thromboembolism has to be weighed against the risk of bleeding. Based on various everyday situations in clinical routine, the purpose of the present expert recommendations is to provide appropriate perioperative and periinterventional management for patients with atrial fibrillation undergoing long-term treatment with the thrombin inhibitor dabigatran. As we currently have no routine laboratory test to measure therapeutic levels of the substance or the risk of bleeding, general measures such as a standardized documentation of the patient’s history, a sufficient time interval between the last preoperative dose and the procedure, and careful control of local hemostasis should be given special attention.
ISSN:0043-5325
1613-7671
DOI:10.1007/s00508-012-0166-5