Mueller matrix retinal imager with optimized polarization conditions

A new Mueller matrix polarimeter was used to image the retinas of normal subjects. Light from a linearly polarized 780 nm laser was passed through a system of variable retarders and scanned across the retina. Light returned from the eye passed through a second system of retarders and a polarizing be...

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Bibliographic Details
Published in:Optics express 2008-12, Vol.16 (26), p.21339-21354
Main Authors: Twietmeyer, K M, Chipman, R A, Elsner, A E, Zhao, Y, VanNasdale, D
Format: Article
Language:English
Subjects:
Algorithms
Calibration
Diagnostic Imaging - methods
Diagnostic Techniques, Ophthalmological
Equipment Design
Humans
Light
Microscopy, Polarization - methods
Models, Statistical
Ocular Physiological Phenomena
Optic Nerve - anatomy & histology
Optics and Photonics
Reproducibility of Results
Retina - anatomy & histology
Retina - physiology
Vision, Ocular
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Summary:A new Mueller matrix polarimeter was used to image the retinas of normal subjects. Light from a linearly polarized 780 nm laser was passed through a system of variable retarders and scanned across the retina. Light returned from the eye passed through a second system of retarders and a polarizing beamsplitter to two confocal detection channels. Optimization of the polarimetric data reduction matrix was via a condition number metric. The accuracy and repeatability of polarization parameter measurements were within +/- 5%. The magnitudes and orientations of retardance and diattenuation, plus depolarization, were measured over 15 degrees of retina for 15 normal eyes.
ISSN:1094-4087
1094-4087
DOI:10.1364/OE.16.021339