Excellence in biomedical research: ubiquitin family proteins and grid cells

[...]the vast majority of the prize money is intended to fund the ongoing research in the recipients' laboratory. [...]the work of Stefan Jentsch and his colleagues challenged the common belief that ubiquitin functioned exclusively in protein degradation pathways and opened a new, exciting fiel...

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Bibliographic Details
Published in:EMBO molecular medicine 2011-02, Vol.3 (2), p.67-68
Main Authors: Funk, Anneke, Rossier, Bernard
Format: Article
Language:English
Subjects:
Animals
Behavior, Animal - physiology
Biomedical research
Biomedical Research - trends
Brain - cytology
Brain - physiology
Brain research
DNA repair
Editorial
Humans
Medicine
Memory
Neurons - physiology
Neurosciences
Proteasome Endopeptidase Complex - metabolism
Proteins
Researchers
Ubiquitin
Ubiquitin - metabolism
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Summary:[...]the vast majority of the prize money is intended to fund the ongoing research in the recipients' laboratory. [...]the work of Stefan Jentsch and his colleagues challenged the common belief that ubiquitin functioned exclusively in protein degradation pathways and opened a new, exciting field that studies the relationship between ubiquitin family proteins and DNA repair pathways. [...]they made seminal discoveries, for example showing that grid cells and the outputs of the respective circuits are connected to memory networks in the hippocampus and determine how memory is deposited in this region.
ISSN:1757-4676
1757-4684
DOI:10.1002/emmm.201000117