Social Relationships and Health: Is Feeling Positive, Negative, or Both (Ambivalent) About Your Social Ties Related to Telomeres?

• Published in: Health psychology 2012-11, Vol.31 (6), p.789-796
• Main Authors: Uchino, Bert N., Cawthon, Richard M., Smith, Timothy W., Light, Kathleen C., McKenzie, Justin, Carlisle, McKenzie, Gunn, Heather, Birmingham, Wendy, Bowen, Kimberly
• Format: Article
• Language: English
• Subjects: Aged; Biological and medical sciences; Emotions; Female; Fundamental and applied biological sciences. Psychology; Health; Health Status; Human; Humans; Illness and personality; Interpersonal Relations; Interpersonal Relationships; Male; Middle Aged; Morbidity; Morbidity-Mortality; Personality, behavior and health; Physical Health; Psychology and medicine; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Risk Factors; Social networks; Social relationships; Telomere - ultrastructure; Telomere Shortening; Telomeres; Women
• ISSN: 0278-6133; 1930-7810
• DOI: 10.1037/a0026836

Objectives: The quality of one's personal relationships has been linked to morbidity and mortality across different diseases. As a result, it is important to examine more integrative mechanisms that might link relationships across diverse physical health outcomes. In this study, we examine associations between relationships and telomeres that predict general disease risk. These questions are pursued in the context of a more comprehensive model of relationships that highlights the importance of jointly considering positive and negative aspects of social ties. Method: One hundred thirty-six individuals from a community sample (ages 48 to 77 years) completed the social relationships index, which allows a determination of relationships that differ in their positive and negative substrates (i.e., ambivalent, supportive, aversive, indifferent). Telomere length was determined from peripheral blood mononuclear cells via quantitative polymerase chain reaction. Results: Participants who had a higher number of ambivalent ties in their social networks evidenced shorter telomeres. These results were independent of other relationship types (e.g., supportive) and standard control variables (e.g., age, health behaviors, and medication use). Gender moderated the links between ambivalent ties and telomere length, with these associations seen primarily in women. Follow-up analyses revealed that the links between ambivalent ties and telomeres were primarily due to friendships, parents, and social acquaintances. Conclusion: Consistent with epidemiological findings, these data highlight a novel and integrative biological mechanism by which social ties may affect health across diseases and further suggest the importance of incorporating positivity and negativity in the study of specific relationships and physical health.