Adrenal insufficiency secondary to inappropriate oral administration of topical exogenous steroids presenting with hypercalcaemia

A 59-year-old Caucasian gentleman presented with malaise, fatigue and proximal muscle weakness. He had history of long-standing roseate psoriasis treated with topical clobetasol propionate (dermovate). On admission, he had significant postural hypotension, and hypercalcaemia. Endocrinological invest...

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Bibliographic Details
Published in:BMJ case reports 2012-06, Vol.2012 (jun21 1), p.bcr0320125983-bcr0320125983
Main Authors: Bhatti, Rahila Sarwar, Flynn, Michael D
Format: Article
Language:English
Subjects:
Adrenal glands
Adrenal Insufficiency - chemically induced
Adrenal Insufficiency - complications
Adrenal Insufficiency - drug therapy
Clobetasol - administration & dosage
Clobetasol - adverse effects
Europe (West)
Glucocorticoids - administration & dosage
Glucocorticoids - adverse effects
Humans
Hydrocortisone - therapeutic use
Hypercalcemia - etiology
Male
Middle Aged
Potassium
Psoriasis - drug therapy
Reminder of Important Clinical Lesson
Self Medication - adverse effects
Steroids
White
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Summary:A 59-year-old Caucasian gentleman presented with malaise, fatigue and proximal muscle weakness. He had history of long-standing roseate psoriasis treated with topical clobetasol propionate (dermovate). On admission, he had significant postural hypotension, and hypercalcaemia. Endocrinological investigation revealed hypercalcaemia, a serum cortisol of
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr.03.2012.5983