Integrating Research on Thyroid Cancer after Chernobyl — The Chernobyl Tissue Bank

Abstract The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood or early adolescence. In response to the scientific interest in studying the molecular biology of thyroid cancer after Chernobyl, the Chernobyl...

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Bibliographic Details
Published in:Clinical oncology (Royal College of Radiologists (Great Britain)) 2011-05, Vol.23 (4), p.276-281
Main Authors: Thomas, G.A, Bethel, J.A, Galpine, A, Mathieson, W, Krznaric, M, Unger, K
Format: Article
Language:English
Subjects:
Chernobyl
Chernobyl Nuclear Accident
Data Collection
Female
Hematology, Oncology and Palliative Medicine
Humans
Male
Neoplasms, Radiation-Induced - blood
Neoplasms, Radiation-Induced - etiology
Neoplasms, Radiation-Induced - pathology
radiation
Radioactive Hazard Release
Radiology
thyroid cancer
Thyroid Neoplasms - blood
Thyroid Neoplasms - etiology
Thyroid Neoplasms - pathology
Tissue Banks
Ukraine
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Summary:Abstract The only unequivocal radiological effect of the Chernobyl accident on human health is the increase in thyroid cancer in those exposed in childhood or early adolescence. In response to the scientific interest in studying the molecular biology of thyroid cancer after Chernobyl, the Chernobyl Tissue Bank was established. The project is supported by the governments of Ukraine and Russia, and financially supported (in total around US$3million) by the European Commission, the National Cancer Institute of the USA and the Sasakawa Memorial Health Foundation of Japan. The project began collecting a variety of biological samples from patients on 1 October 1988, and has supplied material to 21 research projects in Japan, the USA and Europe. The establishment of the Chernobyl Tissue Bank has facilitated co-operation between these research projects and the combination of clinical and research data provides a paradigm for cancer research in the molecular biological age.
ISSN:0936-6555
1433-2981
DOI:10.1016/j.clon.2011.01.503