Effect of Clarithromycin in Inflammatory Markers of Patients with Ventilator-Associated Pneumonia and Sepsis Caused by Gram-Negative Bacteria: Results from a Randomized Clinical Study

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Published in:Antimicrobial Agents and Chemotherapy 2012-07, Vol.56 (7), p.3819-3825
Main Authors: SPYRIDAKI, Aikaterini, RAFTOGIANNIS, Maria, KOTANIDOU, Anastasia, ORFANOS, Stylianos E, VAN DER MEER, Jos W. M, NETEA, Mihai G, GIAMARELLOS-BOURBOULIS, Evangelos J, ANTONOPOULOU, Anastasia, TSAGANOS, Thomas, ROUTSI, Christina, BAZIAKA, Fotini, KARAGIANNI, Vassiliki, MOUKTAROUDI, Maria, KOUTOUKAS, Pantelis, PELEKANOU, Aimilia
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antigen presentation
Apoptosis
Apoptosis - drug effects
B7-2 Antigen - blood
Bacterial diseases
Bacterial sepsis
Biological and medical sciences
Blood
CD40 antigen
CD40 Ligand - blood
CD86 antigen
Clarithromycin
Clarithromycin - therapeutic use
Clinical Therapeutics
Clinical trials
Double-Blind Method
General aspects
Gram-Negative Bacteria
Gram-Negative Bacteria - drug effects
Gram-Negative Bacteria - pathogenicity
Human bacterial diseases
Human infectious diseases. Experimental studies and models
Humans
Immunotherapy
Infectious diseases
Inflammation
Interleukin 10
Interleukin 6
Interleukin-10 - blood
Interleukin-6 - blood
Leukocytes (neutrophilic)
Medical sciences
Monocytes
Pharmacology. Drug treatments
Pneumonia
Pneumonia, Ventilator-Associated
Pneumonia, Ventilator-Associated - blood
Pneumonia, Ventilator-Associated - drug therapy
Sepsis
Sepsis - blood
Sepsis - drug therapy
Septic shock
Tumor necrosis factor- alpha
Tumor Necrosis Factor-alpha - blood
ventilator-associated pneumonia
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.05798-11