Evidence of Rabies Virus Exposure among Humans in the Peruvian Amazon

In May of 2010, two communities (Truenococha and Santa Marta) reported to be at risk of vampire bat depredation were surveyed in the Province Datem del Marañón in the Loreto Department of Perú. Risk factors for bat exposure included age less than or equal to 25 years and owning animals that had been...

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Bibliographic Details
Published in:The American journal of tropical medicine and hygiene 2012-08, Vol.87 (2), p.206-215
Main Authors: GILBERT, Amy T, PETERSEN, Brett W, RECUENCO, Sergio, NIEZGODA, Michael, GOMEZ, Jorge, LAGUNA-TORRES, V. Alberto, RUPPRECHT, Charles
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Animals
Antibodies, Viral - blood
Biological and medical sciences
Child
Child, Preschool
Chiroptera - virology
Disease Outbreaks
Female
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Peru - epidemiology
Rabies - blood
Rabies - epidemiology
Rabies - virology
Rabies virus
Rabies virus - isolation & purification
Rural Population
Seroepidemiologic Studies
Young Adult
Zoonoses - epidemiology
Zoonoses - virology
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Summary:In May of 2010, two communities (Truenococha and Santa Marta) reported to be at risk of vampire bat depredation were surveyed in the Province Datem del Marañón in the Loreto Department of Perú. Risk factors for bat exposure included age less than or equal to 25 years and owning animals that had been bitten by bats. Rabies virus neutralizing antibodies (rVNAs) were detected in 11% (7 of 63) of human sera tested. Rabies virus ribonucleoprotein (RNP) immunoglobulin G (IgG) antibodies were detected in the sera of three individuals, two of whom were also seropositive for rVNA. Rabies virus RNP IgM antibodies were detected in one respondent with no evidence of rVNA or RNP IgG antibodies. Because one respondent with positive rVNA results reported prior vaccination and 86% (six of seven) of rVNA-positive respondents reported being bitten by bats, these data suggest nonfatal exposure of persons to rabies virus, which is likely associated with vampire bat depredation.
ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.2012.11-0689