A patient with primary Burkitt's lymphoma of the postnasal space: case report

Burkitt's lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt's...

Full description

Saved in:
Bibliographic Details
Published in:Head & neck oncology 2012-06, Vol.4 (1), p.33-33, Article 33
Main Authors: Upile, Tahwinder, Jerjes, Waseem, Abiola, Jesuloba, Kafas, Panagiotis, Sandison, Ann, Hamdoon, Zaid, Al-Khawalde, Mohammed, Radhi, Hani
Format: Article
Language:English
Subjects:
Abdomen
Aged
Burkitt Lymphoma - diagnosis
Burkitt Lymphoma - pathology
Case Report
Colleges & universities
Consent
Drug therapy
Humans
Immunohistochemistry
In Situ Hybridization
Lymphoma
Male
Maxillofacial surgery
Surgery
Tomography
University colleges
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Burkitt's lymphoma is a highly aggressive lymphoma. The endemic form is present with Epstein - Barr virus. The most common sites are the mandible, facial bones, kidneys, gastrointestinal tract, ovaries, breast and extra-nodal sites. We present the first reported case of a primary Burkitt's lymphoma of the postnasal space occurring in an elderly Caucasian male. A 72-year-old Caucasian male farmer presented with a 6-week history of a productive cough and a painless left sided cervical swelling. Examination of the neck revealed a 5 cm by 5 cm hard mass in the left anterior triangle. A CT scan of the head and neck showed a soft tissue swelling in the postnasal space. Histology of the postnasal space mass showed squamous mucosa infiltrated by a high grade lymphoma. Immunohistochemical staining and in situ hybridisation confirmed the tumour to be Epstein - Barr virus Ribonucleic acid negative suggesting this was a rare sporadic form of the tumour presenting in a location that is atypical for the clinical subtype and age of the patient. This is the first reported case of sporadic Burkitt's lymphoma of the postnasal space of an elderly Caucasian male in the absence of Epstein - Barr virus or human immunodeficiency virus infection and further serves to illustrate the diversity of histological subtypes of malignancies that may develop at this concealed site.
ISSN:1758-3284
1758-3284
DOI:10.1186/1758-3284-4-33