Study of electrophysiological ischemic events during coronary angioplasty

The electrophysiological and mechanical events that follow transient therapeutic coronary artery balloon occlusion were analyzed in five patients. A marked (mean, 60 msec) decrease in the repolarization time of the left ventricular ischemic zone (assessed indirectly from endocardial monophasic actio...

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Bibliographic Details
Published in:Texas Heart Institute journal 1984-03, Vol.11 (1), p.24-30
Main Authors: DONALDSON, R. M, TAGGART, P, BENNETT, J. G, RICKARDS, A. F
Format: Article
Language:English
Subjects:
Biological and medical sciences
Cardiology. Vascular system
Coronary heart disease
Heart
Medical sciences
Original Communications
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Summary:The electrophysiological and mechanical events that follow transient therapeutic coronary artery balloon occlusion were analyzed in five patients. A marked (mean, 60 msec) decrease in the repolarization time of the left ventricular ischemic zone (assessed indirectly from endocardial monophasic action potential [MAP] recordings) ensued within 6 to 10 beats of occlusion. Abnormalities in left ventricular relaxation occurred almost simultaneously and preceded contraction abnormalities. A shift in the ST segment in the electrocardiogram (ECG) usually followed within the next 5 to 10 beats. An increase in heart rate (approximately 10 beats per minute) appeared last in the sequence of events. Angina was a variable parameter, frequently absent. Thus, intracavitary recordings of the electrical and mechanical changes are sensitive indicators of the early ischemic changes that follow coronary occlusion, and may be used to assess the effects of therapeutic interventions on events resulting from a myocardial perfusion deficit.
ISSN:0730-2347
1526-6702