Selective non-covalent triggered release from liposomes

A zinc(II)-dipicolylamine coordination complex selectively associates with anionic liposomes, including sterically protected PEGylated liposomes, and causes rapid leakage of encapsulated contents.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2012-08, Vol.48 (65), p.8123-8125
Main Authors: Plaunt, Adam J, Courbanou, Meghan B, Cuison, Katrina D, Harmatys, Kara M, Smith, Bradley D
Format: Article
Language:English
Subjects:
Amines - chemistry
Anions - chemistry
Coordination Complexes - chemistry
Delayed-Action Preparations - chemistry
Fluoresceins - administration & dosage
Fluorescent Dyes - administration & dosage
Liposomes - chemistry
Phospholipids - chemistry
Picolinic Acids - chemistry
Polyethylene Glycols - chemistry
Zinc - chemistry
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Description
Summary:A zinc(II)-dipicolylamine coordination complex selectively associates with anionic liposomes, including sterically protected PEGylated liposomes, and causes rapid leakage of encapsulated contents.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc32962j