Mechanism of suppression in Drosophila. VII. Correlation between disappearance of an isoacceptor of tyrosine tRNA and activation of the vermilion locus

The possibility that tyrosine tRNA modifies the catalytic activity of tryptophan oxygenase that is produced by the vermilion mutant (v) in Drosophila melanogaster is reconsidered. Dietary conditions can modify the ratio of the two major isoacceptors of tyrosine tRNA: one condition allows 85–90% to e...

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Bibliographic Details
Published in:Nucleic acids research 1978-07, Vol.5 (7), p.2391-2404
Main Author: Jacobson, K B
Format: Article
Language:English
Subjects:
Animals
Diet
Drosophila melanogaster
Drosophila melanogaster - genetics
Eye Color
Guanosine - analogs & derivatives
RNA, Transfer - genetics
RNA, Transfer - pharmacology
Suppression, Genetic
Temperature
Tryptophan Oxygenase - antagonists & inhibitors
Tryptophan Oxygenase - genetics
Tyrosine
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Summary:The possibility that tyrosine tRNA modifies the catalytic activity of tryptophan oxygenase that is produced by the vermilion mutant (v) in Drosophila melanogaster is reconsidered. Dietary conditions can modify the ratio of the two major isoacceptors of tyrosine tRNA: one condition allows 85–90% to exist as the second isoacceptor, and another condition allows
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/5.7.2391