Fluorescence imaging agents in cancerology

One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection requests specific recognition. Tumor markers have to be ideally present on the surface of cancer cells. Their targeting with ligands coupled to imaging agents...

Full description

Saved in:
Bibliographic Details
Published in:Radiology and oncology 2010-09, Vol.44 (3), p.142-148
Main Authors: Paganin-Gioanni, Aurélie, Bellard, Elisabeth, Paquereau, Laurent, Ecochard, Vincent, Golzio, Muriel, Teissié, Justin
Format: Article
Language:English
Subjects:
Review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:One of the major challenges in cancer therapy is to improve early detection and prevention using novel targeted cancer diagnostics. Detection requests specific recognition. Tumor markers have to be ideally present on the surface of cancer cells. Their targeting with ligands coupled to imaging agents make them visible/detectable. Fluorescence imaging is a newly emerging technology which is becoming a complementary medical method for cancer diagnosis. It allows detection with a high spatio-temporal resolution of tumor markers in small animals and in clinical studies. In this review, we focus on the recent outcome of basic studies in the design of new approaches (probes and devices) used to detect tumor cells by fluorescence imaging.
ISSN:1318-2099
1581-3207
0485-893X
DOI:10.2478/v10019-010-0031-y