Serum lipids, lipoproteins and sex-hormone binding globulin in breast cancer

Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein (HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically proven cases of breast cancer along with...

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Bibliographic Details
Published in:Indian journal of clinical biochemistry 2001-01, Vol.16 (1), p.101-105
Main Authors: Ray, A, Dayalu Naik, S L, Bahadur, A K, Pasha, S T, Rautela, R S, Sharma, B K
Format: Article
Language:English
Subjects:
Breast cancer
Brief Communications
Cholesterol
Diet
Hormones
Lipids
Low density lipoprotein
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Summary:Serum levels of various lipid parameters, i.e., triglycerides, total cholesterol, alpha lipoprotein or high density lipoprotein (HDL)-cholesterol and beta lipoprotein or low density lipoprotein (LDL)-cholesterol were measured in a total of 138 histologically proven cases of breast cancer along with 146 control women. The mean levels of serum triglycerides, total cholesterol and LDL-cholesterol were found to be significantly higher in breast cancer cases as compared to controls. However, lower mean levels of serum HDL-cholesterol and sex-hormone binding glubulin (SHBG) were observed in breast cancer patients than the control subjects. The results indicate a probable relation between serum lipids and the activity of sex-hormones. Moreover, the study reflects an overall disturbance of lipid metabolism in the pathological process of breast cancer.
ISSN:0970-1915
0974-0422
DOI:10.1007/BF02867576