Interleukin-1 receptor antagonist gene polymorphism and obesity: A pilot study from north India

The main adverse consequences of excess bodyweight are cardiovascular disease, type II diabetes, and several cancers, IL-1Ra serum concentration has been reported earlier to increase in human obesity and it is therefore assumed that the polymorphism of IL-1Ra may influence cytokine production. We de...

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Bibliographic Details
Published in:Indian journal of clinical biochemistry 2007-03, Vol.22 (1), p.61-64
Main Authors: Manchanda, P K, Bid, H K, Achyut, B R, Mittal, B, Srivastava, N, Mittal, R D
Format: Article
Language:English
Subjects:
Genes
Genotype & phenotype
Obesity
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Summary:The main adverse consequences of excess bodyweight are cardiovascular disease, type II diabetes, and several cancers, IL-1Ra serum concentration has been reported earlier to increase in human obesity and it is therefore assumed that the polymorphism of IL-1Ra may influence cytokine production. We designed this study to investigate whether the IL-1Ra polymorphism was associated with obesity. A total number of 103 individuals; 19 lean (BMI
ISSN:0970-1915
0974-0422
DOI:10.1007/BF02912883