Pronuclear and morphological features as a cumulative score to select embryos in ICSI (intracytoplasmic sperm injection) cycles according to sperm origin

To analyze best parameter to select embryos according to sperm origin in ICSI cycles. One hundred seventy-two ICSI cycles were divided among three different groups: A (ejaculated spermatozoa from nonmale factor infertility), B (ejaculated spermatozoa from oligospermia), and C (spermatozoa from azoos...

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Bibliographic Details
Published in:Journal of assisted reproduction and genetics 2003, Vol.20 (1), p.1-7
Main Authors: ROSSI-FERRAGUT, Lia Mara, IACONELLI, Assumpto JR, AOKI, Tsutomu, CHAGAS ROCHA, Claudia, DOS SANTOS, Daniela Regina, FIRMBACH PASQUALOTTO, Fabio, BORGES, Edson JR
Format: Article
Language:English
Subjects:
Abortion, Spontaneous
Biological and medical sciences
Birth control
Cell Nucleolus - ultrastructure
Cleavage Stage, Ovum
Ejaculation
Embryo Implantation
Embryo Transfer
Epididymis - physiology
Female
Gynecology. Andrology. Obstetrics
Humans
Male
Medical sciences
Oligospermia
Pregnancy
Pregnancy Rate
Sperm Injections, Intracytoplasmic - methods
Spermatozoa - physiology
Sterility. Assisted procreation
Testis - physiology
Zygote - ultrastructure
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Summary:To analyze best parameter to select embryos according to sperm origin in ICSI cycles. One hundred seventy-two ICSI cycles were divided among three different groups: A (ejaculated spermatozoa from nonmale factor infertility), B (ejaculated spermatozoa from oligospermia), and C (spermatozoa from azoospermia). Embryos were divided on Day 1 into two patterns: S0 (pronuclei (PN) aligned and close with normal arrangement of nucleoli) and S1 (when these characteristics were absent) and also on transfer day according to morphological features. Relationships of PN patterns related to sperm origin were noted. More S0 embryos were detected with better sperm quality. Higher number of good quality embryos was obtained when male factor was absent. Ejaculated and epididymal spermatozoa provide better quality embryos than do testicular spermatozoa. PN classification associated with transfer day morphology is valuable additional noninvasive criterion for elective embryo transfer, mainly in the cases with severe male factor.
ISSN:1058-0468
1573-7330
DOI:10.1023/A:1021286119979