Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations

On the basis of numerical simulations of the partial McAllister-Noble-Tsien equations quantitatively describing the dynamics of electrical processes in conductive cardiac Purkinje fibers we reveal unusual - soliton-like - regimes of interaction of nonlinear excitation pulses governing the heart cont...

Full description

Saved in:
Bibliographic Details
Published in:Journal of biological physics 1999-06, Vol.25 (2-3), p.149-164
Main Authors: Aslanidi, O V, Mornev, O A
Format: Article
Language:English
Subjects:
Biophysics
Cardiology
Heart
Simulation
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c378t-d68f9ad2944821591e87805313f81b4c8e117c4183e7be186d12d5800d2cb65d3
cites
container_end_page 164
container_issue 2-3
container_start_page 149
container_title Journal of biological physics
container_volume 25
creator Aslanidi, O V
Mornev, O A
description On the basis of numerical simulations of the partial McAllister-Noble-Tsien equations quantitatively describing the dynamics of electrical processes in conductive cardiac Purkinje fibers we reveal unusual - soliton-like - regimes of interaction of nonlinear excitation pulses governing the heart contraction rhythm: reflection of colliding pulses instead of their annihilation. The phenomenological mechanism of the reflection effects is that in a narrow (but finite) range of the system parameters the traveling pulse presents a doublet consisting of a high-amplitude leader followed by a low-amplitude subthreshold wave. Upon collisions of pulses the leaders are annihilated, but subthreshold waves summarize becoming superthreshold and initiating two novel echo-pulses traveling in opposite directions. The phenomenon revealed presents an analogy to the effect of reflection of colliding nerve pulses, predicted recently, and can be of use in getting insight into the mechanisms of heart rhythm disturbances.
doi_str_mv 10.1023/A:1005119218136
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3455967</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2136875781</sourcerecordid><originalsourceid>FETCH-LOGICAL-c378t-d68f9ad2944821591e87805313f81b4c8e117c4183e7be186d12d5800d2cb65d3</originalsourceid><addsrcrecordid>eNpdUU1v1DAQtRCIbhfO3JDFqT0EPHacOD1UqqoWKlXiAJwjx57seuvYi50guPPD6y4FAaf5evPmzQwhr4C9BcbFu4szYEwCdBwUiOYJWYFsRcUa1T0lK8Y6XnzWHJHjnHesxIrL5-SIC1HLpqtX5Oen6N0cQ-XdHdKEGzdhpjpYit-Nm_XsYqD7xeeH4ujRHBInaLbxlLpAt3GKGwwYl0yNTtZpU-DpzoUd0tENmPJZ6cyLnzONIw3LhMkZ7Wl20-IP_PkFeTbqMuLlo12TL9dXny8_VLcf399cXtxWRrRqrmyjxk5b3tW14iA7QNUqJgWIUcFQG4UAralBCWwHBNVY4FYqxiw3QyOtWJPzX7z7ZZjQGgxz0r7fJzfp9KOP2vX_VoLb9pv4rS_Xkl3TFoKTR4IUvy6Y535y2aD3-nCBHrjirOaqvGZN3vwH3cUlhbJe30omWi7kA-j134L-KPn9H3EP476UhQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>750372352</pqid></control><display><type>article</type><title>Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations</title><source>Open Access: PubMed Central</source><source>Springer Link</source><creator>Aslanidi, O V ; Mornev, O A</creator><creatorcontrib>Aslanidi, O V ; Mornev, O A</creatorcontrib><description>On the basis of numerical simulations of the partial McAllister-Noble-Tsien equations quantitatively describing the dynamics of electrical processes in conductive cardiac Purkinje fibers we reveal unusual - soliton-like - regimes of interaction of nonlinear excitation pulses governing the heart contraction rhythm: reflection of colliding pulses instead of their annihilation. The phenomenological mechanism of the reflection effects is that in a narrow (but finite) range of the system parameters the traveling pulse presents a doublet consisting of a high-amplitude leader followed by a low-amplitude subthreshold wave. Upon collisions of pulses the leaders are annihilated, but subthreshold waves summarize becoming superthreshold and initiating two novel echo-pulses traveling in opposite directions. The phenomenon revealed presents an analogy to the effect of reflection of colliding nerve pulses, predicted recently, and can be of use in getting insight into the mechanisms of heart rhythm disturbances.</description><identifier>ISSN: 0092-0606</identifier><identifier>EISSN: 1573-0689</identifier><identifier>DOI: 10.1023/A:1005119218136</identifier><identifier>PMID: 23345694</identifier><language>eng</language><publisher>Netherlands: Springer Nature B.V</publisher><subject>Biophysics ; Cardiology ; Heart ; Simulation</subject><ispartof>Journal of biological physics, 1999-06, Vol.25 (2-3), p.149-164</ispartof><rights>Kluwer Academic Publishers 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-d68f9ad2944821591e87805313f81b4c8e117c4183e7be186d12d5800d2cb65d3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455967/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3455967/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23345694$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aslanidi, O V</creatorcontrib><creatorcontrib>Mornev, O A</creatorcontrib><title>Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations</title><title>Journal of biological physics</title><addtitle>J Biol Phys</addtitle><description>On the basis of numerical simulations of the partial McAllister-Noble-Tsien equations quantitatively describing the dynamics of electrical processes in conductive cardiac Purkinje fibers we reveal unusual - soliton-like - regimes of interaction of nonlinear excitation pulses governing the heart contraction rhythm: reflection of colliding pulses instead of their annihilation. The phenomenological mechanism of the reflection effects is that in a narrow (but finite) range of the system parameters the traveling pulse presents a doublet consisting of a high-amplitude leader followed by a low-amplitude subthreshold wave. Upon collisions of pulses the leaders are annihilated, but subthreshold waves summarize becoming superthreshold and initiating two novel echo-pulses traveling in opposite directions. The phenomenon revealed presents an analogy to the effect of reflection of colliding nerve pulses, predicted recently, and can be of use in getting insight into the mechanisms of heart rhythm disturbances.</description><subject>Biophysics</subject><subject>Cardiology</subject><subject>Heart</subject><subject>Simulation</subject><issn>0092-0606</issn><issn>1573-0689</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNpdUU1v1DAQtRCIbhfO3JDFqT0EPHacOD1UqqoWKlXiAJwjx57seuvYi50guPPD6y4FAaf5evPmzQwhr4C9BcbFu4szYEwCdBwUiOYJWYFsRcUa1T0lK8Y6XnzWHJHjnHesxIrL5-SIC1HLpqtX5Oen6N0cQ-XdHdKEGzdhpjpYit-Nm_XsYqD7xeeH4ujRHBInaLbxlLpAt3GKGwwYl0yNTtZpU-DpzoUd0tENmPJZ6cyLnzONIw3LhMkZ7Wl20-IP_PkFeTbqMuLlo12TL9dXny8_VLcf399cXtxWRrRqrmyjxk5b3tW14iA7QNUqJgWIUcFQG4UAralBCWwHBNVY4FYqxiw3QyOtWJPzX7z7ZZjQGgxz0r7fJzfp9KOP2vX_VoLb9pv4rS_Xkl3TFoKTR4IUvy6Y535y2aD3-nCBHrjirOaqvGZN3vwH3cUlhbJe30omWi7kA-j134L-KPn9H3EP476UhQ</recordid><startdate>19990601</startdate><enddate>19990601</enddate><creator>Aslanidi, O V</creator><creator>Mornev, O A</creator><general>Springer Nature B.V</general><general>Kluwer Academic Publishers</general><scope>NPM</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PADUT</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19990601</creationdate><title>Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations</title><author>Aslanidi, O V ; Mornev, O A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-d68f9ad2944821591e87805313f81b4c8e117c4183e7be186d12d5800d2cb65d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Biophysics</topic><topic>Cardiology</topic><topic>Heart</topic><topic>Simulation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aslanidi, O V</creatorcontrib><creatorcontrib>Mornev, O A</creatorcontrib><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Research Library China</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of biological physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aslanidi, O V</au><au>Mornev, O A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations</atitle><jtitle>Journal of biological physics</jtitle><addtitle>J Biol Phys</addtitle><date>1999-06-01</date><risdate>1999</risdate><volume>25</volume><issue>2-3</issue><spage>149</spage><epage>164</epage><pages>149-164</pages><issn>0092-0606</issn><eissn>1573-0689</eissn><abstract>On the basis of numerical simulations of the partial McAllister-Noble-Tsien equations quantitatively describing the dynamics of electrical processes in conductive cardiac Purkinje fibers we reveal unusual - soliton-like - regimes of interaction of nonlinear excitation pulses governing the heart contraction rhythm: reflection of colliding pulses instead of their annihilation. The phenomenological mechanism of the reflection effects is that in a narrow (but finite) range of the system parameters the traveling pulse presents a doublet consisting of a high-amplitude leader followed by a low-amplitude subthreshold wave. Upon collisions of pulses the leaders are annihilated, but subthreshold waves summarize becoming superthreshold and initiating two novel echo-pulses traveling in opposite directions. The phenomenon revealed presents an analogy to the effect of reflection of colliding nerve pulses, predicted recently, and can be of use in getting insight into the mechanisms of heart rhythm disturbances.</abstract><cop>Netherlands</cop><pub>Springer Nature B.V</pub><pmid>23345694</pmid><doi>10.1023/A:1005119218136</doi><tpages>16</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0092-0606
ispartof Journal of biological physics, 1999-06, Vol.25 (2-3), p.149-164
issn 0092-0606
1573-0689
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3455967
source Open Access: PubMed Central; Springer Link
subjects Biophysics
Cardiology
Heart
Simulation
title Soliton-like regimes and excitation pulse reflection (echo) in homogeneous cardiac purkinje fibers: results of numerical simulations
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T21%3A14%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Soliton-like%20regimes%20and%20excitation%20pulse%20reflection%20(echo)%20in%20homogeneous%20cardiac%20purkinje%20fibers:%20results%20of%20numerical%20simulations&rft.jtitle=Journal%20of%20biological%20physics&rft.au=Aslanidi,%20O%20V&rft.date=1999-06-01&rft.volume=25&rft.issue=2-3&rft.spage=149&rft.epage=164&rft.pages=149-164&rft.issn=0092-0606&rft.eissn=1573-0689&rft_id=info:doi/10.1023/A:1005119218136&rft_dat=%3Cproquest_pubme%3E2136875781%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c378t-d68f9ad2944821591e87805313f81b4c8e117c4183e7be186d12d5800d2cb65d3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=750372352&rft_id=info:pmid/23345694&rfr_iscdi=true