Comparing effects of kyphoplasty, vertebroplasty, and non-surgical management in a systematic review of randomized and non-randomized controlled studies

• Published in: European spine journal 2012-09, Vol.21 (9), p.1826-1843
• Main Authors: Papanastassiou, Ioannis D., Phillips, Frank M., Van Meirhaeghe, Jan, Berenson, James R., Andersson, Gunnar B. J., Chung, Gary, Small, Brent J., Aghayev, Kamran, Vrionis, Frank D.
• Format: Article
• Language: English
• Subjects: Balloons; Bone surgery; Cement; Clinical trials; Compression; Controlled Clinical Trials as Topic; Extravasation; Fractures; Fractures, Compression - rehabilitation; Fractures, Compression - surgery; Humans; Kyphoplasty; Kyphosis; Medicine; Medicine & Public Health; Neurosurgery; Osteoporosis; Osteoporotic Fractures - rehabilitation; Osteoporotic Fractures - surgery; Pain; Pain - epidemiology; Pain - etiology; Quality of life; Review; Review Article; Reviews; Risk factors; Spinal Fractures - rehabilitation; Spinal Fractures - surgery; Spine; Surgical Orthopedics; Vertebrae; Vertebroplasty
• ISSN: 0940-6719; 1432-0932
• DOI: 10.1007/s00586-012-2314-z

Purpose To determine if differences in safety or efficacy exist between balloon kyphoplasty (BKP), vertebroplasty (VP) and non-surgical management (NSM) for the treatment of osteoporotic vertebral compression fractures (VCFs). Methods As of February 1, 2011, a PubMed search (key words: kyphoplasty, vertebroplasty) resulted in 1,587 articles out of which 27 met basic selection criteria (prospective multiple-arm studies with cohorts of ≥20 patients). This systematic review adheres to preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Results Pain reduction in both BKP (−5.07/10 points, P