Planned Neck Dissection Following Radiation Treatment for Head and Neck Malignancy

Introduction. Optimal therapy for patients with metastatic neck disease remains controversial. Neck dissection following radiotherapy has traditionally been used to improve locoregional control. Methods. A retrospective review of 28 patients with node-positive head and neck malignancy treated with p...

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Bibliographic Details
Published in:International Journal of Otolaryngology 2012-01, Vol.2012 (2012), p.527-531
Main Authors: Brake, M. K., Dautremont, J. F., Thompson, G., Trites, J., Hart, R. D., Taylor, S. Mark
Format: Article
Language:English
Subjects:
Cancer
Care and treatment
Chemotherapy
Nuclear radiation
Radiotherapy
Surgery
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Summary:Introduction. Optimal therapy for patients with metastatic neck disease remains controversial. Neck dissection following radiotherapy has traditionally been used to improve locoregional control. Methods. A retrospective review of 28 patients with node-positive head and neck malignancy treated with planned neck dissection following radiotherapy between January 2002 and December 2005 was performed to assess treatment outcomes. Results. Median interval to neck dissection was 9.6 weeks with a median number of 21 + 9 lymph nodes per specimen. Ten of 31 (32%) neck dissection specimens demonstrated evidence of residual carcinoma. Overall survival at two years was 85%; five-year overall survival was 65%. Concurrent chemotherapy did not impact the presence of residual neck disease. Conclusion. Based on the frequency of residual malignancy in the neck of patients treated with primary radiotherapy, a planned, postradiotherapy neck dissection should be strongly advocated for all patients with advanced-stage neck disease.
ISSN:1687-9201
1687-921X
DOI:10.1155/2012/954203