Analysis of Gleason grade and scores in 90 Nigerian Africans with prostate cancer during the period 1994 to 2004

Objectives: To determine the relative frequency of prostate cancer among surgical specimens, and among prostate specimens received at the pathology department ,University Hospital Calabar. Methods: Histology records were reviewed for the following: total number of histology specimens received; total...

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Bibliographic Details
Published in:African health sciences 2012-03, Vol.12 (1), p.69-73
Main Authors: Ugare, UG, Bassey, IE, Jibrin, PG, Ekanem, IA
Format: Article
Language:English
Subjects:
Adenocarcinoma - epidemiology
Adenocarcinoma - pathology
Adenocarcinoma - surgery
Age Distribution
Aged
Aged, 80 and over
Biopsy, Needle
Health and Medicine
Hospitals
Hospitals, Teaching
Humans
Incidence
Male
Men
Middle Aged
Neoplasm Grading - statistics & numerical data
Nigeria - epidemiology
Prostate cancer
prostate, cancer, analysis, histologic, pattern, role, grade
Prostatectomy
Prostatic Neoplasms - epidemiology
Prostatic Neoplasms - pathology
Prostatic Neoplasms - surgery
Retrospective Studies
Tumors
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Summary:Objectives: To determine the relative frequency of prostate cancer among surgical specimens, and among prostate specimens received at the pathology department ,University Hospital Calabar. Methods: Histology records were reviewed for the following: total number of histology specimens received; total number of prostate specimens; total number of prostate cancer; and the total number of cancers in males during the study period. Histology sections 4-5microns thick were cut from paraffin blocks and stained by Haematoxylin and Eosin (H&E). Histopathologic specimens were classified using the grading system of tumour differentiation described by Gleason and associates. Results: One hundred and twenty three cancers of the prostate were received, constituting 2% of the total surgical specimens and 31% of prostate specimens. Thirty three cases (27%) could not be analyzed; therefore the study is based on 90 prostate cancer specimens. Eighty nine (99%) cases were epithelial tumours (adenocarcinoma.) There was a single mesenchymal tumour (rhabdomyosarcoma) (1%). The commonest grade in this study was the high grade (Gleason grade IV). Conclusions: We observed that prostate cancer is a common among males (all sites) diagnosed at the University Hospital Calabar, with a peak incidence between the ages of 61 - 70 years (seventh decade).
ISSN:1680-6905
1729-0503