Impact of changes of positive end-expiratory pressure on functional residual capacity at low tidal volume ventilation during general anesthesia

Purpose Several reports in the literature have described the effects of positive end-expiratory pressure (PEEP) level upon functional residual capacity (FRC) in ventilated patients during general anesthesia. This study compares FRC in mechanically low tidal volume ventilation with different PEEP lev...

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Bibliographic Details
Published in:Journal of anesthesia 2012-10, Vol.26 (5), p.664-669
Main Authors: Satoh, Daizoh, Kurosawa, Shin, Kirino, Wakaba, Wagatsuma, Toshihiro, Ejima, Yutaka, Yoshida, Akiko, Toyama, Hiroaki, Nagaya, Kei
Format: Article
Language:English
Subjects:
Abdomen - surgery
Aged
Analysis
Anesthesia
Anesthesia, General - methods
Anesthesiology
Blood gases
Critical Care Medicine
Emergency Medicine
Female
Functional Residual Capacity - physiology
Health aspects
Heart beat
Hemodynamics
Humans
Intensive
Lung - metabolism
Lung - physiology
Male
Medicine
Medicine & Public Health
Original
Original Article
Oxygen - metabolism
Pain Medicine
Patient compliance
Positive-Pressure Respiration - methods
Pulmonary Gas Exchange - physiology
Respiration
Respiration, Artificial - methods
Tidal Volume - physiology
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Summary:Purpose Several reports in the literature have described the effects of positive end-expiratory pressure (PEEP) level upon functional residual capacity (FRC) in ventilated patients during general anesthesia. This study compares FRC in mechanically low tidal volume ventilation with different PEEP levels during upper abdominal surgery. Methods Before induction of anesthesia (awake) for nine patients with upper abdominal surgery, a tight-seal facemask was applied with 2 cmH 2 O pressure support ventilation and 100 % O 2 during FRC measurements conducted on patients in a supine position. After tracheal intubation, lungs were ventilated with bilevel airway pressure with a volume guarantee (7 ml/kg predicted body weight) and with an inspired oxygen fraction (FIO 2 ) of 0.4. PEEP levels of 0, 5, and 10 cmH 2 O were used. Each level of 5 and 10 cmH 2 O PEEP was maintained for 2 h. FRC was measured at each PEEP level. Results FRC awake was significantly higher than that at PEEP 0 cmH 2 O ( P  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-012-1411-9