Transthoracic fine-needle aspiration biopsy of the lungs using a C-arm cone-beam CT system: diagnostic accuracy and post-procedural complications

The purpose of our study was to evaluate the diagnostic accuracy of transthoracic fine-needle aspiration biopsy (TFNAB) using a C-arm cone-beam CT (CBCT) system and to assess risk factors for immediate post-procedural complications in patients with lung lesions. From October 2007 to April 2009, 94 T...

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Bibliographic Details
Published in:British journal of radiology 2012-06, Vol.85 (1014), p.e217-e222
Main Authors: Lee, W J, Chong, S, Seo, J S, Shim, H J
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biopsy, Fine-Needle - adverse effects
Biopsy, Fine-Needle - methods
Cone-Beam Computed Tomography
Female
Humans
Lung - pathology
Lung Diseases - pathology
Male
Middle Aged
Pneumothorax - epidemiology
Pneumothorax - etiology
Postoperative Hemorrhage - epidemiology
Postoperative Hemorrhage - etiology
Reproducibility of Results
Risk Factors
Thorax
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Summary:The purpose of our study was to evaluate the diagnostic accuracy of transthoracic fine-needle aspiration biopsy (TFNAB) using a C-arm cone-beam CT (CBCT) system and to assess risk factors for immediate post-procedural complications in patients with lung lesions. From October 2007 to April 2009, 94 TFNAB procedures using a C-arm system were studied in 91 patients with pulmonary lesions a chest CT scans. We retrospectively reviewed the patients' radiological and histopathological findings. We evaluated the lesion size, lesion abutted to pleura and presence or absence of emphysema along the needle path, lesion depth, visibility of target lesion and patient's position. Pneumothorax and pulmonary haemorrhage were assessed after TFNAB. Overall diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were analysed. In 94 TFNAB procedures, 58 lesions were malignant and 36 were benign. The sensitivity, specificity, PPV, NPV and overall diagnostic accuracy rate of TFNAB were 93.1%, 100%, 100%, 90% and 97.9%, respectively. Pneumothorax was developed in 24 procedures. None of the parameters showed significant impact on the frequency of the pneumothorax. Overall haemorrhage occurred in 43 procedures. The incidence of overall haemorrhage was higher in patients with smaller lesions, longer pleural distance and pleural abutted lesions (p
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr/64727750