Validity of predicting left ventricular end systolic pressure changes following an acute bout of exercise

Abstract Objectives Left ventricular end systolic pressure (LV ESP) is important in assessing left ventricular performance and is usually derived from prediction equations. It is unknown whether these equations are accurate at rest or following exercise in a young, healthy population. Design Measure...

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Bibliographic Details
Published in:Journal of science and medicine in sport 2013-01, Vol.16 (1), p.71-75
Main Authors: Kappus, Rebecca M, Ranadive, Sushant M, Yan, Huimin, Lane, Abbi D, Cook, Marc D, Hall, Grenita, Harvey, I. Shevon, Wilund, Kenneth R, Woods, Jeffrey A, Fernhall, Bo
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aerobics
Applanation tonometry
Birth control
Blood Pressure Determination - methods
Diastole
End systolic pressure
Exercise
Exercise Test
Female
Health
Heart
Heart rate
Humans
Intubation
Left ventricular function
Male
Manometry
Mathematical Concepts
Measurement
Mortality
Physical fitness
Physical Medicine and Rehabilitation
Population
Predictive Value of Tests
Rest
Sport science
Sports Medicine
Stress
Systole
Validity
Veins & arteries
Ventricular Function, Left - physiology
Young Adult
Youth
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Summary:Abstract Objectives Left ventricular end systolic pressure (LV ESP) is important in assessing left ventricular performance and is usually derived from prediction equations. It is unknown whether these equations are accurate at rest or following exercise in a young, healthy population. Design Measured LV ESP vs. LV ESP values from the prediction equations were compared at rest, 15 min and 30 min following peak aerobic exercise in 60 participants. Methods LV ESP was obtained by applanation tonometry at rest, 15 min post and 30 min post peak cycle exercise. Results Measured LV ESP was significantly lower ( p < 0.05) at all time points in comparison to the two calculated values. Measured LV ESP decreased significantly from rest at both the post15 and post30 time points ( p < 0.05) and changed differently in comparison to the calculated values (significant interaction; p < 0.05). The two LV ESP equations were also significantly different from each other ( p < 0.05) and changed differently over time (significant interaction; p < 0.05). Conclusions The two commonly used prediction equations did not accurately predict either resting or post exercise LV ESP in a young, healthy population. Thus, LV ESP needs to be individually determined in young, healthy participants. Non-invasive measurement through applanation tonometry appears to allow for a more accurate determination of LV ESP.
ISSN:1440-2440
1878-1861
DOI:10.1016/j.jsams.2012.05.003