Staged hepatectomy for bilobar colorectal hepatic metastases

Abstract Objectives This study describes the management of patients with bilobar colorectal liver metastases (CRLM). Methods A retrospective collection of data on all patients with CRLM who were considered for staged resection ( n = 85) from January 2003 to January 2011 was performed. Patients who u...

Full description

Saved in:
Bibliographic Details
Published in:HPB (Oxford, England) England), 2012-11, Vol.14 (11), p.782-789
Main Authors: Jamal, Mohammad H, Hassanain, Mazen, Chaudhury, Prosanto, Tran, Tung T, Wong, Stephanie, Yousef, Yasmine, Jozaghi, Yelda, Salman, Ayat, Jabbour, Samir, Simoneau, Eve, Al-Abbad, Saleh, Al-Jiffry, Murad, Arena, Goffredo, Kavan, Petr, Metrakos, Peter
Format: Article
Language:English
Subjects:
Aged
Chi-Square Distribution
Colorectal Neoplasms - mortality
Colorectal Neoplasms - pathology
Disease-Free Survival
Female
Gastroenterology and Hepatology
Hepatectomy - adverse effects
Hepatectomy - methods
Hepatectomy - mortality
Humans
Kaplan-Meier Estimate
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - mortality
Liver Neoplasms - secondary
Liver Neoplasms - surgery
Logistic Models
Male
Middle Aged
Multivariate Analysis
Odds Ratio
Original
Quebec
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Objectives This study describes the management of patients with bilobar colorectal liver metastases (CRLM). Methods A retrospective collection of data on all patients with CRLM who were considered for staged resection ( n = 85) from January 2003 to January 2011 was performed. Patients who underwent one hepatic resection were considered to have had a failed staged resection (FSR), whereas those who underwent a second or third hepatic resection to produce a cure were considered to have had a successful staged resection (SSR). Survival was calculated from the date of diagnosis of liver metastases. Complete follow-up and dates of death were obtained from the Government of Quebec population database. Results Median survival was 46 months (range: 30–62 months) in the SSR group and 22 months (range: 19–29 months) in the FSR group. Rates of 5-year survival were 42% and 4% in the SSR and FSR groups, respectively. Fifteen of the 19 patients who remained alive at the last follow-up date belonged to the SSR group. Conclusions In patients in whom staged resection for bilobar CRLM is feasible, surgery would appear to offer benefit.
ISSN:1365-182X
1477-2574
DOI:10.1111/j.1477-2574.2012.00543.x