Safety and Pharmacokinetics of Intravaginal Rings Delivering Tenofovir in Pig-Tailed Macaques

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Published in:Antimicrobial Agents and Chemotherapy 2012-11, Vol.56 (11), p.5952-5960
Main Authors: MOSS, John A, MALONE, Amanda M, HENDRY, R. Michael, GUENTHNER, Patricia, HOLDER, Angela, MARTIN, Amy, MCNICHOLL, Janet, MITCHELL, James, PAU, Chou-Pong, SRINIVASAN, Priya, SMITH, James M, BAUM, Marc M, SMITHY, Thomas J, BUTKYAVICHENE, Irina, CORTEZ, Cassandra, GILMAN, Joshua, KENNEDY, Sean, KOPIN, Etana, NGUYEN, Cali, SINHA, Preetha
Format: Article
Language:English
Subjects:
Adenine
Adenine - analogs & derivatives
Adenine - pharmacokinetics
Administration, Intravaginal
Animals
Antibiotics. Antiinfectious agents. Antiparasitic agents
Biological and medical sciences
Contraceptive Devices, Female
Contraceptive Devices, Female - veterinary
Cytokines - secretion
Delayed-Action Preparations
Delayed-Action Preparations - pharmacokinetics
Female
Half-Life
Lymphocytes - chemistry
Macaca nemestrina
Medical sciences
Organophosphonates
Organophosphonates - pharmacokinetics
Pharmacology
Pharmacology. Drug treatments
Reverse Transcriptase Inhibitors
Reverse Transcriptase Inhibitors - pharmacokinetics
Tenofovir
Vagina
Vagina - cytology
Vagina - drug effects
Vagina - metabolism
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.01198-12